RAB0393
Human Oncostatin M (OSM) ELISA Kit
for serum, plasma, cell culture supernatants and urine
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About This Item
Código UNSPSC:
41116158
NACRES:
NA.32
Productos recomendados
reactividad de especies
human
envase
kit of 96 wells (12 strips x 8 wells)
técnicas
ELISA: suitable
capture ELISA: suitable
entrada
sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 1.37-1000 pg/mL
método de detección
colorimetric
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
Información sobre el gen
human ... OSM(5008)
Categorías relacionadas
Descripción general
Oncostatin M (OSM) is a multifunctional hematopoietic cytokine that belongs to the interleukin-6 (IL-6) cytokine family. Human OSM is produced by activated T lymphocytes and monocytes mainly during inflammatory disorders. OSM acts as a cell growth modulator. In addition, it also participates in low-density lipoprotein (LDL) receptor upregulation and induction of hematopoietic factors. OSM contributes to the inflammatory process, autoimmunity, and immunopathogenesis of cancers.
Inmunógeno
Recombinant Human OSM
Aplicación
The Human Oncostatin M (OSM) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Oncostatin M in serum, plasma, cell culture supernatants, and urine.
Otras notas
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Los componentes del kit también están disponibles por separado
Referencia del producto
Descripción
SDS
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Met. Corr. 1
Código de clase de almacenamiento
8A - Combustible corrosive hazardous materials
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A Grenier et al.
Blood, 93(4), 1413-1421 (1999-02-09)
Oncostatin M (OSM) is an interleukin-6 (IL-6) family cytokine known in particular to induce the synthesis of acute-phase proteins by hepatocytes. Because human polymorphonuclear neutrophils (PMN) can secrete numerous cytokines, the potential production of OSM by PMN was investigated. Highly
Y Ma et al.
Nucleic acids research, 27(23), 4649-4657 (1999-11-11)
Oncostatin M (OSM), an IL-6 subfamily cytokine, inhibits proliferation and causes morphological changes in many tumor cell lines. GM-CSF, phorbol-12-myristate-13-acetate (PMA), and lipopolysaccharide (LPS) induce OSM expression. To investigate the mechanisms governing OSM promoter activity, we have cloned and partially
Oncostatin M: A mysterious cytokine in cancers.
Masjedi, et al.
International Immunopharmacology, 90, 107158-107158 (2021)
Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL-6 in OSM-driven pulmonary inflammation.
Botelho FM
Journal of Immunology, 191, 1453-1464 (2013)
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