Saltar al contenido
Merck

R3250

Sigma-Aldrich

Acetato de retinil

synthetic, matrix dispersion, 475,000-650,000 USP units/g

Sinónimos:

Acetato de retinol, Acetato de vitamina A

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Fórmula empírica (notación de Hill):
C22H32O2
Número de CAS:
Peso molecular:
328.49
Beilstein/REAXYS Number:
1915439
EC Number:
MDL number:
UNSPSC Code:
12352205
eCl@ss:
34058009
PubChem Substance ID:
NACRES:
NA.79
En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

synthetic

Quality Level

form

matrix dispersion

specific activity

475,000-650,000 USP units/g

color

yellow

mp

57-58 °C

storage temp.

−20°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

¿Está buscando productos similares? Visita Guía de comparación de productos

General description

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.[1]

Application

Retinyl acetate has been used:
  • a control diet to study its effect at different developmental periods in fish larvae[2]
  • to study its inhibitory effects on Mycobacterium avium subspecies paratuberculosis (MAP) strains[3]
  • as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk[4]

Biochem/physiol Actions

Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as required. Retinyl acetate is used in a wide range of biological applications.[1] It acts as a chemopreventive agent.[5] Retinyl acetate also has antineoplastic property.[6]

Physical form

Dispersion in cornstarch-gelatin matrix. Oil dispersible

Analysis Note

Activity based on HPLC comparison to USP standard.

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Laure A N Villeneuve et al.
The British journal of nutrition, 95(4), 677-687 (2006-03-31)
The effect of the feeding period on larval development was investigated in European sea bass larvae by considering the expression level of some genes involved in morphogenesis. Larvae were fed a control diet except during three different periods (period A:
Intake of high levels of vitamin A and polyunsaturated fatty acids during different developmental periods modifies the expression of morphogenesis genes in European sea bass (Dicentrarchus labrax)
Villeneuve LAN, et al.
The British Journal of Nutrition, 95(4), 677-687 (2006)
A survey of vitamin A and D contents of fortified fluid milk in Ontario
Faulkner H, et al.
Journal of Dairy Science, 83(6), 1210-1216 (2000)
Vitamins A & D inhibit the growth of mycobacteria in radiometric culture
Greenstein RJ, et al.
PLoS ONE, 7(1), e29631-e29631 (2012)
Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid
Udeani GO, et al.
Cancer Research, 57(16), 3424-3428 (1997)

Questions

  1. What is the solubility information for this product? It is not dissolved in hexane, heptane, acetone, isopropyl alcohol, water, and absolute ethanol; even left overnight on stir plate.

    1 answer
    1. R3250 is classified as a matrix dispersion. This product contains gelatin, sugar, modified food starch, and other components to make it convenient as an "oil dispersible material," which will not dissolve in chloroform. The gelatin and starch components in this product would not be soluble but will be dispersed or suspended in the oil. For a soluble retinol acetate product, recommended Product No. is R4632, Retinol Acetate all trans, which is soluble in chloroform (50 mg/ml), yielding a clear, yellow-green solution. Product No. R4632 is also soluble in ethanol.

      Helpful?

Reviews

No rating value

Active Filters

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico