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Merck

N8000

Sigma-Aldrich

1-Naphthyl butyrate

esterase substrate, ≥99% (GC), liquid

Sinónimos:

Butanoic acid 1-naphthyl ester, Butyric acid 1-naphthyl ester

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About This Item

Fórmula lineal:
CH3CH2CH2CO2C10H7
Número de CAS:
Peso molecular:
214.26
Beilstein/REAXYS Number:
2558646
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

product name

1-Naphthyl butyrate, esterase substrate

description

esterase substrate

Quality Level

assay

≥99% (GC)

form

liquid

refractive index

n20/D 1.571 (lit.)

bp

125-130 °C/1 mmHg (lit.)

solubility

ethanol: 100 mg/mL, clear, colorless to faintly yellow

density

1.091 g/mL at 20 °C (lit.)

storage temp.

−20°C

SMILES string

CCCC(=O)Oc1cccc2ccccc12

InChI

1S/C14H14O2/c1-2-6-14(15)16-13-10-5-8-11-7-3-4-9-12(11)13/h3-5,7-10H,2,6H2,1H3

InChI key

XIVJNRXPRQKFRZ-UHFFFAOYSA-N

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Application

1-Naphthyl butyrate has been used as a substrate for esterase activity in sheep body louse Bovicola ovis and in chromogenic staining of flounder fish samples.

Biochem/physiol Actions

1-Naphthyl butyrate also called α-naphthyl butyrate is a substrate for esterase enzyme. α-naphthyl butyrate aids in assessing α-naphthyl butyrate esterase activity in monocytes and lymphocytes.

Substrates

Esterase substrate.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

143.6 °F - closed cup

flash_point_c

62 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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J Yourno et al.
Blood, 60(1), 24-29 (1982-07-01)
Lymphocytes from a case of B-cell chronic lymphocytic leukemia (CLL) were obtained in a highly purified state from a therapeutic leukapheresis preparation. The CLL lymphocytes showed a fine, scattered, granular pattern of nonspecific esterase cytochemical reactivity with either alpha-naphthyl acetate
Y Kaneko et al.
Blood, 60(2), 389-399 (1982-08-01)
We studied the karyotype in 26 children with ANLL, which was diagnosed on the basis of the FAB classification. Clonal chromosome abnormalities were found in 21 of 26 patients. Four patients, including 3 with Down's syndrome, had AML(M1). Nine patients
P M Mattes et al.
Toxicology and applied pharmacology, 114(1), 71-76 (1992-05-01)
Carboxylesterase activity in the rat nasal mucosa plays an important role in the response of this tissue to certain toxic inhaled esters. We have examined this activity in extracts of both Fischer-344 rat and human nasal tissue using the substrate
J Yourno et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(6), 727-733 (1986-06-01)
Monocytes contain a characteristic, prominent set of membrane-bound nonspecific esterases with a slightly acid isoelectric point. These esterases are also detected at modest levels in some granulocyte preparations. They are not apparent in lymphocytes. Among 18 fresh myeloid leukemias and
Identification of alpha-naphthyl butyrate esterase as a plasma membrane ectoenzyme of monocytes and as a discrete intracellular membrane-bounded organelle in lymphocytes.
Bozdech MJ and Bainton DF
The Journal of Experimental Medicine, 153(1), 182-195 (1981)

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