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Merck

N5521

Sigma-Aldrich

α(2→3,6) Neuraminidase from Clostridium perfringens (C. welchii)

recombinant, expressed in E. coli, buffered aqueous solution, ≥250 units/mg protein

Sinónimos:

Acyl-Neuraminyl Hydrolase, Sialidase

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About This Item

Comisión internacional de enzimas:
Número MDL:
Código UNSPSC:
12352204
NACRES:
NA.32

recombinante

expressed in E. coli

Nivel de calidad

Formulario

buffered aqueous solution

actividad específica

≥250 units/mg protein

mol peso

~41 kDa

actividad extraña

proteases, none detected

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

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Acciones bioquímicas o fisiológicas

Releases α(2→3)- and α(2→6)-linked N-acetylneuraminic acid from complex oligosaccharides.

Envase

Provided with 5× reaction buffer (250 mM sodium phosphate, pH 6.0).

Definición de unidad

One unit will hydrolyze 1 μmole of 4-methylumbelliferyl α-D-N-acetylneuraminide per min at pH 5.0 at 37 °C

Forma física

Solution in 20 mM Tris-HCl, pH 7.5, and 25 mM NaCl.

Nota de preparación

Expressed in glycosidase-free hosts.

Pictogramas

Health hazard

Palabra de señalización

Danger

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Resp. Sens. 1

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Andrew T Pavia
Infectious disease clinics of North America, 27(1), 157-175 (2013-02-13)
Respiratory viruses have long been appreciated as a cause of community acquired pneumonia (CAP), particularly among children, people with serious medical comorbidities, and military recruits. They are increasingly recognized as a cause of CAP among adults. Polymerase chain reaction-based testing
Quanjiao Chen et al.
PloS one, 8(1), e54334-e54334 (2013-01-26)
Two surface glycoproteins of influenza virus, haemagglutinin (HA) and neuraminidase (NA), play opposite roles in terms of their interaction with host sialic acid receptors. HA attaches to sialic acid on host cell surface receptors to initiate virus infection while NA
Kao-Tan Chen et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(20), 3068-3073 (2013-01-15)
To isolate and identify active neuraminidase constituents of Polygonum cuspidatum against influenza A (H1N1) influenza virus. On the basis of the bioassay-guided fractionation,such chromatographic methods as silica gel, sephadex LH-20 and HPLC were adopted to isolate active constituents of extracts
Ramaiah Arunachalam et al.
Interdisciplinary sciences, computational life sciences, 4(4), 282-290 (2013-01-29)
The aim of the present investigation was to discover the genetic relationships of 2009 pandemic novel influenza A/H1N1 virus (NIV) external antigens Hemagglutinin (HA) and Neuraminidase (NA) with other influenza viruses by performing phylogenetic, comparative and statistical analyses. Phylogenetic trees
Johan Nordholm et al.
The Journal of biological chemistry, 288(15), 10652-10660 (2013-03-01)
Interactions that facilitate transmembrane domain (TMD) dimerization have been identified mainly using synthetic TMDs. Here, we investigated how inherent properties within natural TMDs modulate their interaction strength by exploiting the sequence variation in the nine neuraminidase subtypes (N1-N9) and the

Artículos

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.

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