M3895

Mucin from bovine submaxillary glands

Type I-S

• Sinónimos: MUC
• Número de CAS: 84195-52-8
• Número CE: 282-357-4
• Número MDL: MFCD00131629
• Código UNSPSC: 12352202
• NACRES: NA.61

Propiedades

• origen biológico: bovine submaxillary glands
• Nivel de calidad: 200
• tpo: Type I-S
• Formulario: powder
• composición: Bound sialic acids, 9-24%
• técnicas: electrophoresis: suitable
• Nº de acceso UniProt: P98091
• temp. de almacenamiento: −20°C
• Información sobre el gen: cow ... BSM(286841)

Descripción

Descripción general

Mucin from bovine submaxillary glands is encoded by two bovine submaxillary BSM genes. It is present in the saliva and interacts with air and food. Mucin comprises three major domains namely N- and C terminal and the glycosylated proline, threonine and serine (PTS domain) central domain. The sialic acid contributes to 30% of the molecular weight of mucin. The central domain has many tandem repeats.

Aplicación

Mucin from bovine submaxillary glands has been used:

• in the quantification of mucin
• as a component of artificial tear solution
• as a substrate for recombinant sialidase Gardnerella vaginalis
• to investigate a galactose-specific lectin from the red marine alga Ptilota filicina
• to study the characterization of a unique mucin-like glycoprotein secreted by a human endometrial adenocarcinoma cell line (Ishikawa)

Acciones bioquímicas o fisiológicas

Albuminoid substance in mucus which gives it its ropy consistency

Bovine submaxillary mucin (BSM) is thermally stable up to 85°C. The terminal domain regions are key for the adsorption functionality of mucin.

Ligadura / enlace

Similar to M 4503, but produced by Sigma.

Sustratos

Neuraminidase substrate.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)