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H9268

Sigma-Aldrich

Hexadimethrine bromide

≥94% (titration)

Sinónimos:

1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene

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About This Item

Número de CAS:
28728-55-4
MDL number:
MFCD00133397
UNSPSC Code:
41106502
NACRES:
NA.26

Quality Level

200

assay

≥94% (titration)

storage temp.

2-8°C

SMILES string

BrCCCBr.N(CCCCCCN(C)C)(C)C

InChI

1S/C10H24N2.C3H6Br2/c1-11(2)9-7-5-6-8-10-12(3)4;4-2-1-3-5/h5-10H2,1-4H3;1-3H2

InChI key

KZKAYEGOIJEWQB-UHFFFAOYSA-N

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General description

Hexadimethrine bromide is a quaternary ammonium compound which works as a heparin antagonist. It is also involved in the transformation of low molecular weight DNA.

Application

Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.
Hexadimethrine bromide has been used for lentivirus infection in cells. It has been used for infection of cells with retroviral supernatant.

related product

Referencia del producto
Descripción
Precios

08168

Timestrip Plus™ 8 °C

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000228148
MKCV5340
MKCV9880
0000086650
MKCT2743

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Nature communications, 8(1), 1988-1988 (2017-12-08)
Cutaneous melanoma represents the most fatal skin cancer due to its high metastatic capacity. According to the "phenotype switching" model, the aggressive nature of melanoma cells results from their intrinsic potential to dynamically switch from a high-proliferative/low-invasive to a low-proliferative/high-invasive
Molecular pathways regulating pro-migratory effects of Hedgehog signaling.
Hochman E et al.
The Journal of Biological Chemistry, 281, 33860-33860 (2006)
Blood (2013)
Redei GP
Encyclopedia of Genetics, Genomics, Proteomics, and Informatics (2008)
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Examination of Lentiviral Library Efficiency

Small interfering RNAs (siRNAs) are powerful tools for gene expression knockdown, widely used in molecular biology.

Examination of Lentiviral Library Efficiency

Small interfering RNAs (siRNAs) are powerful tools for gene expression knockdown, widely used in molecular biology.

Protocolos

Lentiviral Transduction Protocol

Detailed procedure for how to perform a lentiviral transduction of MISSION shRNA lentiviral particles to achieve a stable long term silencing and phenotypic change.

Lentiviral Transduction Protocol

Detailed procedure for how to perform a lentiviral transduction of MISSION shRNA lentiviral particles to achieve a stable long term silencing and phenotypic change.

Lentiviral Transduction Protocol

Detailed procedure for how to perform a lentiviral transduction of MISSION shRNA lentiviral particles to achieve a stable long term silencing and phenotypic change.

Lentiviral Transduction Protocol

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Ver todo

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