D8821
Dextrano from Leuconostoc mesenteroides
average mol wt 60,000-76,000
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About This Item
Fórmula lineal:
(C6H10O5)n
Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
12352201
NACRES:
NA.25
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origen biológico
bacterial (Leuconostoc mesenteroides)
Nivel de calidad
Formulario
powder
actividad óptica
[α]20/D 190 to 201 °, c = 2% (w/v) in water
mol peso
average mol wt 60,000-76,000
color
white to off-white
mp
483 °C ((901 °F ))
solubilidad
water: 100 mg/mL at 25 °C, colorless to faintly yellow
temp. de almacenamiento
2-8°C
cadena SMILES
O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O
InChI
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
Clave InChI
FZWBNHMXJMCXLU-UHFFFAOYSA-N
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Descripción general
Dextran is an extracellular bacterial polymer of D-glucopyranose. It consists of α-(1→6) linkage in the main chain with a variable amount of α-(1→2), α-(1→3), α-(1→4) branched linkages. Dextran from L. mesenteroides B512F comprises 95% of α- (1→6) linkages and 5% of α-(1→3) branch linkages. Insoluble dextran from L. mesenteroides 1299 contains 63% α-(1→6), 27% of α-(1→2) and 8% of α-(1→3) linkages.
Aplicación
El uso de dextranos como brazos espaciadores largos e hidrófilos mejora el rendimiento de las proteínas inmovilizadas que actúan sobre las macromoléculas.
Dextran from Leuconostoc mesenteroides has been used:
- in resuspension of pellets and in Hanks′ balanced salt solution (HBSS) for the isolation of vascular nuclei from frozen post-mortem brain tissue
- to prepare dextran solution in phosphate buffer saline and to maintain corneal hydration and restore corneal thickness to physiological levels of human eyes
- as a polymer solution in the in situ aqueous two-phase systems (ATPS) formation with lysozyme PEGylation reaction
Acciones bioquímicas o fisiológicas
Dextran is commercially available as a drug, especially as a blood plasma volume expander. This bacterial polysaccharide has several applications, such as adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Dextran is used in the thickening of jam and ice cream in the food industry. It prevents sugar crystallization and retains moisture. This helps in preserving the flavor and appearance of several food items.
Otras notas
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 2
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International journal of biological sciences, 4(6), 379-386 (2008-10-28)
On the basis of high enzyme activity a newly isolated strain of L. mesenteroides CMG713 was selected for dextran production. For maximum yield of dextran, effects of various parameters such as pH, temperature, sucrose concentration and incubation period were studied.
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For reducing the steric hindrance and nonspecific binding of the target DNA, the dextran was used as molecular arms to be immobilized on the surface of magnetic nanoparticles (MNPs). Magnetic separation was used in preparation of dextran-MNPs (DMNPs). Aspartic acid
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