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Merck

C8784

Sigma-Aldrich

Anti-Corticosterone antibody produced in rabbit

whole antiserum, lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

technique(s)

radioimmunoassay: suitable (dextran coated charcoal 3H RIA)

storage temp.

2-8°C

target post-translational modification

unmodified

General description

Corticosterone is a steroid hormone produced mainly in the cortex of adrenal glands. It also known as the stress hormone and has a crucial role in enhancing and suppressing synaptic plasticity and memory processes.Rabbit anti-corticosterone antibody reacts specifically with corticosterone.

Immunogen

Corticosterone-21-Thyroglobulin

Application

Anti-corticosterone antibody can be used to measure total CORT level in serum using radioimmunoassay.

Physical form

The product is provided as a pre-diluted antiserum that has been lyophilized. Each vial contains no more than 20 mg Polyvinylpyrrolidone (PVP).

Reconstitution

Reconstitute with 5 mL buffer: 0.05 M Tris-HCl, pH 8.0, 0.1 M sodium chloride, 0.1% bovine serum albumin, and 0.1% sodium azide. Store this stock at −20 °C. Working dilution (1:10) to be discarded if unused within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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Silvia Liliana Ruiz Roa et al.
Endocrinology, 158(5), 1339-1346 (2017-03-23)
The postnatal synchronization of the circadian variation of the adrenal clock genes in mammals remains unknown. We evaluated the postnatal ontogeny of daily variation of clock genes (Clock/Bmal1/Per1/Per2/Per3/Cry1/Cry2/Rorα/Rev-Erbα) and steroidogenesis-related genes (Star and Mc2r) in rat adrenals and its relationship
Csongor I Vágási et al.
PloS one, 13(2), e0192701-e0192701 (2018-02-13)
Glucocorticoid (GC) hormones are significant regulators of homeostasis. The physiological effects of GCs critically depend on the time of exposure (short vs. long) as well as on their circulating levels (baseline vs. stress-induced). Previous experiments, in which chronic and high
Warren K Hansen et al.
Conservation physiology, 4(1), cow015-cow015 (2016-07-07)
Understanding sources of reproductive variation can inform management and conservation decisions, population ecology and life-history theory. Annual reproductive variation can drive population growth rate and can be influenced by factors from across the annual cycle (known as carry-over effects). The
T J Cole et al.
Genes & development, 9(13), 1608-1621 (1995-07-01)
The role of the glucocorticoid receptor (GR) in glucocorticoid physiology and during development was investigated by generation of GR-deficient mice by gene targeting. GR -/- mice die within a few hours after birth because of respiratory failure. The lungs at
Brenna M G Gormally et al.
Conservation physiology, 8(1), coaa125-coaa125 (2021-01-12)
Physiological metrics are becoming popular tools for assessing individual condition and population health to inform wildlife management and conservation decisions. Corticosterone assays can provide information on how animals cope with individual and habitat-level stressors, and the recent development of feather

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