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Key Documents

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C7020

Supelco

Cefadroxil

analytical standard

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About This Item

Fórmula empírica (notación de Hill):
C16H17N3O5S
Número de CAS:
50370-12-2
Peso molecular:
363.39
EC Number:
256-555-6
MDL number:
MFCD00865091
UNSPSC Code:
41116107
PubChem Substance ID:
24892921
NACRES:
NA.24

grade

analytical standard

Quality Level

200

form

powder or crystals

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C2=O)C(O)=O

InChI

1S/C16H17N3O5S/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24)/t10-,11-,15-/m1/s1

Inchi Key

BOEGTKLJZSQCCD-UEKVPHQBSA-N

General description

Cefadroxil is a broad spectrum cephalosporin antibiotic, widely used in veterinery medicine for the oral treatment of infectious diseases.

Application

Cefadroxil has been used as a standard in the analysis of cefadroxil residues in the samples of domestic sheep milk using penzym enzymatic test method. Cefadroxil may be used as an analytical reference standard for the quantification of the analyte in milk samples using Delvotest photometric technique and in biological samples using high-performance liquid chromatography, respectively.
Cefadroxil has been used as a standard in the analysis of cefadroxil residues in the samples of domestic sheep milk using penzym enzymatic test method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Eunice Kazue Kano et al.
Arzneimittel-Forschung, 58(1), 42-47 (2008-03-29)
Two different cefadroxil (CAS 50370-12-2) formulations were evaluated for their relative bioavailability in 24 healthy volunteers who received a single 500 mg oral dose of each preparation. An open, randomized clinical trial designed as a two-period crossover study with a
Robert Six et al.
Journal of the American Veterinary Medical Association, 233(3), 433-439 (2008-08-05)
To evaluate the efficacy and safety of administration of cefovecin, compared with cefadroxil, for treatment of naturally occurring secondary superficial pyoderma, abscesses, and infected wounds in dogs. Multicenter, randomized, positive-controlled clinical trial. 235 client-owned dogs. Dogs with clinical signs of
Scleredema following scabies infestation.
Amit K Malhotra et al.
Pediatric dermatology, 25(1), 136-138 (2008-02-29)
G Lamba et al.
The West Indian medical journal, 60(3), 346-348 (2012-01-10)
We report a life-threatening anaphylactic reaction to cefadroxil in a 60-year old female with no previous history of allergies to penicillins. Cefadroxil is a first-generation cephalosporin and anaphylactic reactions to it in patients with no previous history of penicillin allergy
Anil K Philip et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 658-666 (2008-01-22)
In the present study, both disintegrating and non-disintegrating polymeric capsular system in achieving delayed as well as improved osmotic flow for the model drug cefadroxil was developed. Asymmetric membrane in membrane capsule (AMMC) was prepared on a glass mold pin
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