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C1426

Sigma-Aldrich

Cesium methanesulfonate

used in patch clamp techniques

Sinónimos:

CsMSF, CsMeS, Methanesulfonic acid cesium salt

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About This Item

Fórmula lineal:
CH3O3SCs
Número de CAS:
2550-61-0
Peso molecular:
228.00
MDL number:
MFCD00075523
UNSPSC Code:
12161700
PubChem Substance ID:
24892412
NACRES:
NA.25

Quality Level

100

form

powder

mp

262-264 °C (lit.)

SMILES string

[Cs+].CS([O-])(=O)=O

InChI

1S/CH4O3S.Cs/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1

InChI key

DJKJXRLREATOMF-UHFFFAOYSA-M

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General description

Cesium methanesulfonate is used as a component of intracellular recording solutions of electrodes for patch clamp techniques in cell electrophysiology studies. Cesium methanesulfonate is used as an current carrier as cesium acts as a potassium (K+) channel blocker, while methanesulfonate is not transported through chloride (Cl-) channels.

Application

Cesium methanesulfonate has been used as a supplement in intracellular solution for the patch clamp recording system.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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L Zhang et al.
Pflugers Archiv : European journal of physiology, 426(3-4), 247-253 (1994-02-01)
Using the whole-cell recording technique, we have examined the slow Ca(2+)-activated afterhyperpolarization (AHP) and its underlying current (IAHP) in hippocampal CA1 neurones of brain slices obtained from mature rats. Specifically we have studied the effects of the anion component of
Diverse voltage-sensitive dyes modulate GABAA receptor function.
Mennerick., S., et al.
The Journal of Neuroscience, 24, 2871-2879 (2010)
An optogenetics- and imaging-assisted simultaneous multiple patch-clamp recording system for decoding complex neural circuits.
Wang G
Nature Protocols, 10, 397-397 (2015)
Justin N Siemian et al.
Scientific reports, 9(1), 12026-12026 (2019-08-21)
A pivotal role of the lateral hypothalamus (LH) in regulating appetitive and reward-related behaviors has been evident for decades. However, the contributions of LH circuits to other survival behaviors have been less explored. Here we examine how lateral hypothalamic neurons
M Ouardouz et al.
Journal of neurophysiology, 77(4), 1939-1949 (1997-04-01)
Whole cell recordings were used in hippocampal slices of young rats to examine unitary inhibitory postsynaptic currents (uIPSCs) evoked in CA1 pyramidal cells at room temperature. Loose cell-attached stimulation was applied to activate single interneurons of different subtypes located in
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