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B5057

Sigma-Aldrich

7-Benzyloxy-4-trifluoromethylcoumarin

≥99% (HPLC), solid

Sinónimos:

7-BFC

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About This Item

Fórmula empírica (notación de Hill):
C17H11F3O3
Peso molecular:
320.26
MDL number:
MFCD01564466
UNSPSC Code:
12161501
PubChem Substance ID:
24891807
NACRES:
NA.47

Nombre del producto

7-Benzyloxy-4-trifluoromethylcoumarin, ≥99% (HPLC), solid

Quality Level

100

assay

≥99% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12

InChI

1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2

InChI key

WVKLERKKJXUPIK-UHFFFAOYSA-N

Gene Information

rat ... Maoa(29253) , Maob(25750)

Application

7-Benzyloxy-4-trifluoromethylcoumarin has been used:

  • in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
  • in O-dealkylation reaction to determine the activity of CYP3A
  • to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)

Biochem/physiol Actions

Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.

Legal Information

Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
MKCT8475
MKCR4344
MKCR4345
MKCR0199
MKCN6112

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