A9555
Monoclonal Anti-Aflatoxin B1 (G1, Q1, B2, G2) antibody produced in mouse
clone AT-B1, ascites fluid
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About This Item
Productos recomendados
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
AT-B1, monoclonal
contains
15 mM sodium azide
technique(s)
ELISA: 1:20,000 using aflatoxin B1-BSA
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Monoclonal anti-Aflatoxin B (mouse IgG1 isotype) is 1 derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.Aflatoxins are a group of naturally occurring fungal toxins (mycotoxins) synthesized by Aspergillus flavus and Aspergillus parasiticus. It is found as contaminants in human and animal food such as corn, peanuts, tree nuts, cottonseed, cereal crops, beans, casssava, milo, sorghum, copra, rice, dried fish and beer.
Immunogen
aflatoxin B -KLH conjugate
Application
Monoclonal Anti-Aflatoxin B1 (G1, Q1, B2, G2) antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and fluorescence polarization assay.
Biochem/physiol Actions
Aflatoxin B (AFB) and its metabolites is known to act as potent carcinogens, mutagens and teratogens, in addition to its toxicity. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry.
Target description
Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Robert J Lee et al.
Scientific reports, 6, 33221-33221 (2016-09-15)
Aflatoxins are mycotoxins secreted by Aspergillus flavus, which can colonize the respiratory tract and cause fungal rhinosinusitis or bronchopulmonary aspergillosis. A. flavus is the second leading cause of invasive aspergillosis worldwide. Because many respiratory pathogens secrete toxins to impair mucociliary
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de Andrade CYT, et al.
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Development of a fluorescence polarization assay for the determination of aflatoxins in grains
Nasir MS and Jolley ME
Journal of Agricultural and Food Chemistry, 50(11), 3116-3121 (2002)
Mycotoxins
Bennett JW, et al.
Clinical Microbiology Reviews, 16(3), 497-497 (2003)
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