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Merck
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Key Documents

A5597

Sigma-Aldrich

Xylene Substitute

greener alternative

Sinónimos:

for microscopy

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About This Item

EC Number:
265-068-8
UNSPSC Code:
12171500
NACRES:
NA.47

form

solution

greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

density

0.723 g/cm3

application(s)

hematology
histology

greener alternative category

, Aligned

storage temp.

2-8°C

General description

Compatible with all tissue processors. May not be compatible with all permanent mounting media.

Application

Xylene Substitute has been used to dewax or de-paraffinize the specimen sections after the staining process.We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing. For more information see www.sigmaaldrich.com/catalog/papers/19608083.

pictograms

FlameHealth hazard
GHS02,GHS08

signalword

Danger

hcodes

H225,H304

Hazard Classifications

Asp. Tox. 1 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

63.0 °F - closed cup

flash_point_c

17.2 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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René J Buesa et al.
Annals of diagnostic pathology, 13(4), 246-256 (2009-07-18)
After the hazardous effects of xylene became indisputable in the 1970s, many potential substitutes became available, some with as many if not more hazards. This article discusses the inadequacy of 5 vegetable oils as substitutes, as well as the characteristics
Jiaming Guo et al.
Biomedical optics express, 11(1), 99-108 (2020-02-06)
Immunohistochemical techniques, such as immunofluorescence (IF) staining, enable microscopic imaging of local protein expression within tissue samples. Molecular profiling enabled by IF is critical to understanding pathogenesis and is often involved in complex diagnoses. A recent innovation, known as microscopy
Kyle Jablonski et al.
PloS one, 15(10), e0237520-e0237520 (2020-10-02)
Gout is the most prevalent inflammatory arthritis. To study the effects of regular physical activity and exercise intensity on inflammation and clinical outcome, we examined inflammatory pathogenesis in an acute model of murine gout and analyzed human gout patient clinical
Jiaming Guo et al.
Scientific reports, 9(1), 14578-14578 (2019-10-12)
Analysis of three-dimensional biological samples is critical to understanding tissue function and the mechanisms of disease. Many chronic conditions, like neurodegenerative diseases and cancers, correlate with complex tissue changes that are difficult to explore using two-dimensional histology. While three-dimensional techniques
Alexandre Ho-Pun-Cheung et al.
British journal of cancer, 122(3), 397-404 (2019-12-04)
Triple-negative breast cancer (TNBC) has a worse prognosis compared with other breast cancer subtypes, and biomarkers to identify patients at high risk of recurrence are needed. Here, we investigated the expression of human epidermal receptor (HER) family members in TNBC
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