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36275

Sigma-Aldrich

Lycopene, Redivivo™

10% FS, ~10% in corn oil, ≥95.0% (sum of isomers)

Sinónimos:

Lycopene, dispersion

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About This Item

Fórmula empírica (notación de Hill):
C40H56
Número de CAS:
502-65-8
Peso molecular:
536.87
EC Number:
232-281-2
MDL number:
MFCD00017350
UNSPSC Code:
12352211
PubChem Substance ID:
329755000
NACRES:
NA.47

Quality Level

100

assay

≥95.0% (sum of isomers)

contains

≤2.5% α-Tocopherol as stabilizer

concentration

~10% in corn oil

storage temp.

2-8°C

SMILES string

C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C

InChI

1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

InChI key

OAIJSZIZWZSQBC-GYZMGTAESA-N

Biochem/physiol Actions

Lycopene is a red phytochemical pigment found in tomatoes. The main carotenoid in human plasma, it is a highly potent antioxidant, the most efficient biological quencher of singlet oxygen, associated with decreased risk of cancer and cardiovascular diseases. Lycopene enhances gap junction communication between cells via upregulation of connexin 43 and reduces profileration of cancer cells in culture. Inhibits cholesterol synthesis and enhances low-density lipoprotein degradation. Lycopene in skin sacrificially protects against UV-induced degradation of β-carotene.

Other Notes

REDIVIVO is a non-toxic, stable formulation of lycopene (10% dispersion in corn oil) that offers convenient handling and is dust-free.

Legal Information

Redivivo is a trademark of DSM Nutritional Products AG

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCBJ9005V
BCCH3373
BCBB1229V
BCBB1229

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USP

USP

1148806

Aceite de maíz

β-Carotene synthetic, ≥93% (UV), powder

Sigma-Aldrich

C9750

β-Carotene

Aceite de maíz analytical standard

Supelco

47112-U

Aceite de maíz

Tamoxifeno ≥99%

Sigma-Aldrich

T5648

Tamoxifeno

Wilhelm Stahl et al.
Skin pharmacology and applied skin physiology, 15(5), 291-296 (2002-09-20)
Upon exposure to UV light photooxidative reactions are initiated which are damaging to biomolecules and affect the integrity of cells and tissues. Photooxidative damage plays a role in pathological processes and is involved in the development of disorders affecting the
J D Ribaya-Mercado et al.
The Journal of nutrition, 125(7), 1854-1859 (1995-07-01)
This placebo-controlled study examined in healthy women the effects of ingestion of a single large dose of beta-carotene (120 mg) on the concentrations of beta-carotene and lycopene in plasma and skin, and the effects of UV light exposure on the
P Di Mascio et al.
Archives of biochemistry and biophysics, 274(2), 532-538 (1989-11-01)
Lycopene, a biologically occurring carotenoid, exhibits the highest physical quenching rate constant with singlet oxygen (kq = 31 X 10(9) M-1 s-1), and its plasma level is slightly higher than that of beta-carotene (kq = 14 X 10(9) M-1 s-1).
Dragan Ilic et al.
Maturitas, 72(4), 269-276 (2012-05-29)
Prostate cancer is a leading cancer affecting men worldwide. Benign prostatic hyperplasia (BPH) is a common disease of the prostate affecting men as they age, and a risk factor for developing prostate cancer. Lycopene is a member of the carotenoid
Dragan Ilic et al.
The Cochrane database of systematic reviews, (11)(11), CD008007-CD008007 (2011-11-11)
Prostate cancer is a common cause of death in developed countries, yet the benefits of screening for prostate cancer still remain controversial. A prostate-specific antigen (PSA) test result greater than 4 ng/mL (nanograms/millilitre) has commonly been used as the cut-off
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