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Merck

Y0001243

Folic acid impurity D

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Pteroic acid

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About This Item

Fórmula empírica (notación de Hill):
C14H12N6O3
Número de CAS:
Peso molecular:
312.28
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

folic acid

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

NC1=NC(=O)C2=NC(CNc3ccc(cc3)C(O)=O)=CNC2=N1

InChI

1S/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21)

InChI key

JOAQINSXLLMRCV-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Folic acid impurity D EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Preparation and purification of pteroic acid from pteroylglutamic acid (folic acid).
J M Scott
Methods in enzymology, 66, 657-660 (1980-01-01)
Sumith A Kularatne et al.
Methods in molecular biology (Clifton, N.J.), 624, 249-265 (2010-03-11)
Nanoparticulate medicines offer the advantage of allowing delivery of large quantities of unmodified drug within the same particle. Nanoparticle uptake by cancer cells can, however, be compromised due to the large size and hydrophilicity of the particle. To circumvent cell
Synthesis of pteroylglutamic acid (liver L. casei factor) and pteroic acid.
M E HULTQUIST et al.
Journal of the American Chemical Society, 70(1), 23-23 (1948-01-01)
X Yan et al.
Journal of molecular biology, 266(5), 1043-1049 (1997-03-14)
Ricin is a potent cytotoxin which has been used widely in the construction of therapeutic agents such as immunotoxins. Recently it has been used by governments and underground groups as a poison. There is interest in identifying and designing effective
Synthesis of pteroylglutamic acid (liver L. casei factor) and pteroic acid.
C W WALLER et al.
Journal of the American Chemical Society, 70(1), 19-22 (1948-01-01)

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