PHR1094

Phenacetin melting point standard

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Phenacetin, 1-Acetyl-p-phenetidin, 4′-Ethoxyacetanilide, N-(4-Ethoxyphenyl)acetamide, p-Acetophenetidide, Acetophenetidin
• Fórmula lineal: CH₃CONHC₆H₄OC₂H₅
• Número de CAS: 62-44-2
• Peso molecular: 179.22
• Beilstein/REAXYS Number: 1869238
• EC Number: 200-533-0
• MDL number: MFCD00009094
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823116
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1514008
• API family: phenacetin
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: ~Approximately 135 °C; 133-136 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CCOc1ccc(NC(C)=O)cc1
• InChI: 1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)
• InChI key: CPJSUEIXXCENMM-UHFFFAOYSA-N

Descripción

General description

Phenacetin is a mild analgesic drug effective for the treatment of mild to moderate pain. Its analgesic property is comparable to that of aspirin.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Phenacetin may be used as a calibration standard for the development of a test for the evaluation of phenacetin by thermal analyzes methods.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Substrate of CYP1A2 and CYP2D6.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC4010 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Información de seguridad

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H350
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable