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Merck

P2125

Supelco

D-Pantethine

analytical standard

Sinónimos:

Bis(N-pantothenylamidoethyl) disulfide, LBF factor, Pantethein oxidized form

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About This Item

Fórmula empírica (notación de Hill):
C22H42N4O8S2
Número de CAS:
Peso molecular:
554.72
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

biological source

synthetic (organic)

Quality Level

grade

analytical standard

assay

≥90%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

application(s)

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

InChI

1S/C22H42N4O8S2/c1-21(2,13-27)17(31)19(33)25-7-5-15(29)23-9-11-35-36-12-10-24-16(30)6-8-26-20(34)18(32)22(3,4)14-28/h17-18,27-28,31-32H,5-14H2,1-4H3,(H,23,29)(H,24,30)(H,25,33)(H,26,34)/t17-,18-/m0/s1

InChI key

DJWYOLJPSHDSAL-ROUUACIJSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Los clientes también vieron

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D H Fisher et al.
Journal of pharmaceutical and biomedical analysis, 15(5), 653-662 (1997-02-01)
In several animal models, preliminary studies have indicated that pantethine may inhibit cataract formation. Therefore, preclinical trials need to be conducted to study the pharmacology of pantethine in the ocular lens and to establish its efficacy. Since pantethine, which is
G Friberg et al.
Current eye research, 15(12), 1182-1190 (1996-12-01)
Solutions of the bovine lens protein gamma B (or gamma II) crystallin at neutral pH in the absence of reducing agents, undergo a slow, partial conversion to a new protein species, gamma IIH. This species is an aggregate composed of
J I Clark et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(26), 15185-15189 (1996-12-24)
The effects of pantethine, glutathione, and selected chemical reagents on the anti-aggregation activity of alpha-crystallin was evaluated. Protein aggregation was monitored by light scattering of solutions of denatured beta L-crystallin or alcohol dehydrogenase (ADH). The ratios of beta L-crystallin/alpha-crystallin and
John I Clark
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1617), 20120104-20120104 (2013-03-27)
Cataract, neurodegenerative disease, macular degeneration and pathologies of ageing are often characterized by the slow progressive destabilization of proteins and their self-assembly to amyloid-like fibrils and aggregates. During normal cell differentiation, protein self-assembly is well established as a dynamic mechanism
H Nomura et al.
Clinical therapeutics, 18(3), 477-482 (1996-05-01)
We compared the efficacy of two antihyperlipidemic drugs and the efficacy of diet plus exercise therapy in the treatment of patients with moderate hypercholesterolemia. The study included 48 patients with moderate hypercholesterolemia (serum total cholesterol [TC], 250 to 320 mg/dL).

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