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N0020000

Nabumetone

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

4-(6-Methoxy-2-naphthyl)-2-butanone

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About This Item

Fórmula empírica (notación de Hill):
C15H16O2
Número de CAS:
42924-53-8
Peso molecular:
228.29
MDL number:
MFCD00079518
UNSPSC Code:
41116107
PubChem Substance ID:
329818390
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

nabumetone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

COc1ccc2cc(CCC(C)=O)ccc2c1

InChI

1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3

InChI key

BLXXJMDCKKHMKV-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nabumetone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Nonselective non-steroidal anti-inflammatory drug (NSAID)

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

N0020020

Nabumetone impurity D, European Pharmacopoeia (EP) Reference Standard

N0020030

Nabumetone impurity F, European Pharmacopoeia (EP) Reference Standard

1449518

Nabumetone, United States Pharmacopeia (USP) Reference Standard

1449530

Nabumetone Related Compound A, United States Pharmacopeia (USP) Reference Standard

08137

2-(6-Methoxynaphthalen-2-yl)acetic acid, pharmaceutical impurity standard

BP358

Nabumetone, British Pharmacopoeia (BP) Reference Standard

BP851

Nabumetone impurity D, British Pharmacopoeia (BP) Reference Standard

PHR3056

Nabumetone, pharmaceutical secondary standard, certified reference material

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Biopharmaceutics & drug disposition, 34(2), 125-136 (2012-12-12)
Diclofenac suppository, a non-steroidal anti-inflammatory drug (NSAID), is used widely in rheumatoid arthritis (RA) patients with severe arthritic pain. As the binding percentage of diclofenac to serum proteins is high, its free (unbound) concentration after rectal administration is low. To
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Recent breakthroughs in creating induced pluripotent stem cells (iPSCs) provide alternative means to obtain embryonic stem-like cells without destroying embryos by introducing four reprogramming factors (Oct3/4, Sox2, and Klf4/c-Myc or Nanog/Lin28) into somatic cells. iPSCs are versatile tools for investigating
Bernard Bannwarth
Drug safety, 31(6), 485-503 (2008-05-20)
Although effective in the treatment of pain associated with rheumatic conditions such as osteoarthritis and rheumatoid arthritis, long-term use of NSAIDs is primarily limited by their association with upper gastrointestinal (GI) toxicity. Adverse effects range from dyspepsia and abdominal pain
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