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Merck

E0900000

Ergocalciferol

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Calciferol, Ercalciol, Ergosterol irradiated, Irradiated ergosterol, Vitamin D2

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About This Item

Fórmula empírica (notación de Hill):
C28H44O
Número de CAS:
Peso molecular:
396.65
Beilstein/REAXYS Number:
1916682
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP

API family

ergocalciferol

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

114-118 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C

InChI

1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1

InChI key

MECHNRXZTMCUDQ-RKHKHRCZSA-N

Gene Information

human ... VDR(7421)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ergocalciferol is a form of vitamin D, synthesized by some plants in the presence of UVB light. It can be obtained from diet intake or supplements.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Simultaneous determination of cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) in foods by selected reaction monitoring
Dimartino G
Journal of AOAC (Association of Official Analytical Chemists) International, 92(2), 511-517 (2002)
Nutrition in the Prevention and Treatment of Disease (2008)
Jean-Yves Reginster
Current medical research and opinion, 21(4), 579-586 (2005-05-19)
Inadequate serum vitamin D is associated with secondary hyperparathyroidism, increased bone turnover, and bone loss, which increased fracture risk. Osteomalacia has also been observed in severe cases. Indeed, vitamin D and calcium are essential components of management strategies for the
G Jones et al.
Physiological reviews, 78(4), 1193-1231 (1998-10-28)
The important reactions that occur to the vitamin D molecule and the important reactions involved in the expression of the final active form of vitamin D are reviewed in a critical manner. After an overview of the metabolism of vitamin
Michael P Boyle et al.
American journal of respiratory and critical care medicine, 172(2), 212-217 (2005-04-30)
Treatment guidelines for vitamin D monitoring and supplementation in cystic fibrosis (CF) have recently been developed and published by a consensus committee, but have not been prospectively tested. To use these guidelines to determine the percentage of adults with CF

Protocolos

Ascentis Express C18 is suitable for routine analysis of fat-soluble vitamins D2 and D3, providing optimized chromatograms.

Ascentis Express C18 is suitable for routine analysis of fat-soluble vitamins D2 and D3, providing optimized chromatograms.

Ascentis Express C18 is suitable for routine analysis of fat-soluble vitamins D2 and D3, providing optimized chromatograms.

Separation of Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard

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