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Merck

BCR157

Benz[a]acridine

BCR®, certified reference material

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About This Item

Fórmula empírica (notación de Hill):
C17H11N
Número de CAS:
Peso molecular:
229.28
Beilstein/REAXYS Number:
9262
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

c1ccc2nc3ccc4ccccc4c3cc2c1

InChI

1S/C17H11N/c1-3-7-14-12(5-1)9-10-17-15(14)11-13-6-2-4-8-16(13)18-17/h1-11H

InChI key

JEGZRTMZYUDVBF-UHFFFAOYSA-N

Analysis Note

For more information please see:
BCR157

Legal Information

BCR is a registered trademark of European Commission

pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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G R Southworth et al.
Archives of environmental contamination and toxicology, 10(5), 561-569 (1981-09-01)
The bioconcentration and metabolism of benz(a)acridine in fathead minnows (Pimephales promelas) was investigated using 14C-labelled benz(a)acridine. The rates of uptake, elimination, and metabolic transformation of benz(a)acridine were estimated in the fish. The equilibrium concentration factor [ratio of benz(a)acridine concentration in
Mutagenicity of diol-epoxides and tetrahydroepoxides of benz(a)acridine and benz(c)acridine in bacteria and in mammalian cells.
A W Wood et al.
Cancer research, 43(4), 1656-1662 (1983-04-01)
N Motohashi et al.
Anticancer research, 12(1), 135-139 (1992-01-01)
Various synthetic derivatives of phenothiazines, benzo[a]phenothiazines and benz[c]acridines were compared for their abilities to induce antiplasmid activity against E. coli F'lac plasmid. Several phenothiazine derivatives were much more potent in antiplasmid activity than benzo[a]phenothiazine- or benz[c]acridine derivatives. Their antiplasmid activity
A D Ayrton et al.
Biochemical pharmacology, 37(23), 4565-4571 (1988-12-01)
The ability of the aza-aromatic polycyclic aromatic hydrocarbons 10-azobenz(a)pyrene and benz(a)acridine to induce the rat hepatic microsomal mixed-function oxidases was compared to that of their non-heterocyclic analogues benz(a)pyrene and benz(a)anthracene respectively. All four hydrocarbons markedly increased the O-deethylations of ethoxyresorufin
Benz[a]acridine.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 32, 123-127 (1983-12-01)

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