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Merck

791725

Sigma-Aldrich

Ácido cítrico

anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.5%

Sinónimos:

2-Hydroxy-propane-1,2,3-tricarboxylic acid

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About This Item

Fórmula lineal:
HOC(COOH)(CH2COOH)2
Número de CAS:
Peso molecular:
192.12
Beilstein/REAXYS Number:
782061
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent
anhydrous

Quality Level

product line

Redi-Dri

assay

≥99.5%

form

crystals

quality

free-flowing

expl. lim.

8 %, 65 °F

impurities

Substances carbonizable by hot sulfuric acid, passes test

ign. residue

≤0.02%

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

mp

153-159 °C (lit.)

anion traces

chloride (Cl-): ≤0.001%
oxalate (C2O42-): passes test (limit about 0.003%)
phosphate (PO43-): ≤0.001%
sulfate (SO42-): ≤0.002%

cation traces

Fe: ≤3 ppm
Pb: ≤2 ppm

functional group

carboxylic acid
hydroxyl

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

KRKNYBCHXYNGOX-UHFFFAOYSA-N

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General description

Citric acid also called 2-hydroxy-propane-1,2,3-tricarboxylic acid, is a component of the tricarboxylic acid cycle in all organisms. Industrial production of citric acid use fungal, yeast and citrus fruit as the major source. Aspergillus niger is majorly used for citric acid production by fermentation Manganese inhibits fermentative production of citric acid Oral supplementation of citric acid promotes tricarboxylic acid cycle and oxidative phosphorylation in mitochondria, attenuating physical fatigue.

Application

Citric acidhas been used as a component of citrate buffer and Fe-free sauton′s medium. It has been used in hybridization chain reaction buffer for preequilibration of coverslips for testes sections.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Two promoters in the esx-3 gene cluster of Mycobacterium smegmatis respond inversely to different iron concentrations in vitro
Fang Z, et al.
BMC Research Notes, 10(1), 426-426 (2017)
Effects of citric acid and L-carnitine on physical fatigue
Sugino T, et al.
Journal of Clinical Biochemistry and Nutrition, 41(3), 224-230 (2007)
Methylene blue exerts a neuroprotective effect against traumatic brain injury by promoting autophagy and inhibiting microglial activation
Zhao M, et al.
Molecular Medicine Reports, 13(1), 13-20 (2016)
Biotechnological production of citric acid
Max B, et al.
Brazilian Journal of Microbiology, 41(4), 862-875 (2010)
A comprehensive roadmap of murine spermatogenesis defined by single-cell RNA-seq
Green CD, et al.
Developmental Cell, 46(5), 651-667 (2018)

Artículos

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

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