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Merck

71210

Sigma-Aldrich

Sodium ethoxide

technical, ≥95% (T)

Sinónimos:

Sodium ethylate

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About This Item

Fórmula lineal:
CH3CH2ONa
Número de CAS:
Peso molecular:
68.05
Beilstein/REAXYS Number:
3593646
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

vapor density

1.6 (vs air)

Quality Level

vapor pressure

<0.1 mmHg ( 20 °C)

grade

technical

assay

≥95% (T)

form

powder

impurities

~2% Na2CO3 and NaOH

SMILES string

[Na+].CC[O-]

InChI

1S/C2H5O.Na/c1-2-3;/h2H2,1H3;/q-1;+1

InChI key

QDRKDTQENPPHOJ-UHFFFAOYSA-N

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General description

Sodium ethoxide (Sodium ethylate) is a sodium alkoxide. It has been synthesized by reacting sodium with ethanol. It undergoes decomposition in the presence of water to afford ethanol and sodium hydroxide. It is widely employed as a strong base in organic synthesis studies.
Sodium ethoxide is an alkoxide salt mainly used as a strong base in organic reactions such as deprotonation, dehydration and dehalogenation.

Application

Sodium ethoxide may be used as a base for the palladium catalyzed cross-coupling of aryl halides and alkenylboranes to synthesize arylated (E)-alkenes.
Sodium ethoxide may be used for the preparation of tricarbonylchloro(glycinato)ruthenium(II) (CORM-3).

pictograms

FlameCorrosion

signalword

Danger

Hazard Classifications

Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1A

supp_hazards

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

wgk_germany

WGK 1

flash_point_f

86.0 °F - closed cup

flash_point_c

30 °C - closed cup


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Whitaker KS and Whitaker DT
e-EROS Encyclopedia of Reagents for Organic Synthesis (2001)
Stereoselective synthesis of arylated (E)-alkenes by the reaction of alk-1-enylboranes with aryl halides in the presence of palladium catalyst.
Miyaura N & Suzuki, A.
Journal of the Chemical Society. Chemical Communications, 19, 866-867 (1979)
James E Clark et al.
Circulation research, 93(2), e2-e8 (2003-07-05)
Carbon monoxide, which is generated in mammals during the degradation of heme by the enzyme heme oxygenase, is an important signaling mediator. Transition metal carbonyls have been recently shown to function as carbon monoxide-releasing molecules (CO-RMs) and to elicit distinct
Eagleson M.
Concise Encyclopedia Chemistry, 997-997 (1994)
N C Luu et al.
Chemical research in toxicology, 13(7), 610-615 (2000-07-18)
Glutathione conjugate formation plays important roles in the detoxification and bioactivation of xenobiotics. A range of nephrotoxic haloalkenes undergo bioactivation that involves glutathione and cysteine S-conjugate formation. The cysteine S-conjugates thus formed may undergo cysteine conjugate beta-lyase-catalyzed biotransformation to form

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