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Merck
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Documentos clave

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2011

Millipore

Bilirubin

solid, bile pigment, Calbiochem®

Sinónimos:

Bilirubin

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About This Item

Fórmula empírica (notación de Hill):
C33H36N4O6
Número de CAS:
635-65-4
Peso molecular:
584.66
Número MDL:
MFCD00005499
Código UNSPSC:
12352200
NACRES:
NA.77

Nombre del producto

Bilirubin, Principal pigment of bile and one of the major end products of hemoglobin decomposition.

Nivel de calidad

100

descripción

RTECS - DU3038000
Merck USA index - 14, 1218

Formulario

solid

fabricante / nombre comercial

Calbiochem®

condiciones de almacenamiento

OK to freeze
protect from light

color

red-brown

solubilidad

chloroform: 1 mg/mL
alkaline solution: soluble

Condiciones de envío

ambient

temp. de almacenamiento

10-30°C

cadena SMILES

[nH]1c(c(c(c1\C=C4/NC(=O)C(=C/4C)C=C)C)CCC(=O)O)Cc2[nH]c(c(c2CCC(=O)O)C)\C=C3/NC(=O)C(=C/3C=C)C

InChI

1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-

Clave InChI

BPYKTIZUTYGOLE-IFADSCNNSA-N

Descripción general

Bilirubin is an orange-yellow bile pigment and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. In adults, the upper limit of the normal range of bilirubin is >1mg/dL. Serum levels of bilirubin in healthy newborns are less than 15 mg/dl. This product corresponds to the unconjugated form.

Acciones bioquímicas o fisiológicas

Bilirubin is reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This pigment aids in coloration in the various forms of jaundice. Bilirubin levels act as biomarkers in liver and blood disorders. Unconjugated form of bilirubin at lower levels serves as a physiological antioxidant. However, increased concentration of bilirubin is toxic and leads to neonatal hyperbilirubinemia in neonates.

Reconstitución

Unstable in basic solutions; reconstitute just prior to use.

Otras notas

Extinction coefficient (454 nm, CHCl3):59,100-62,300 M-1cm-1.
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Target

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

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