1.16177

LiChrospher^® 100 RP-18 (5 µm) HPLC Columns

HPLC sorbent

• Sinónimos: TM=["LiChrospher"] C18 sorbent for HPLC
• UNSPSC Code: 41115709
• NACRES: SB.52

Propiedades

• product name: LiChrospher^® 100 RP-18 (5 µm),
• material: stainless steel column
• agency: suitable for USP L1
• product line: LiChrospher^®
• feature: endcapped: no
• packaging: 1 ea of
• extent of labeling: 21% Carbon loading
• parameter: 60 °C max. temp.
• technique(s): HPLC: suitable; mass spectrometry (MS): suitable (Low - Medium)
• surface area: 350 m²/g
• matrix: fully porous particle
• matrix active group: C18 bonding phase
• particle size: 5 μm
• pore size: 100 Å pore size
• operating pH range: 2-7.5
• bulk density: 200‑400 kg/m³
• separation technique: reversed phase
• storage temp.: no temp limit

Descripción

General description

LiChrospher^® RP-18 is a reliable and versatile traditionally produced spherical silica gel carrier with C-18 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.

Application

• Fast Determination of a Novel Iron Chelate Prototype Used as a Fertilizer by Liquid Chromatography Coupled to a Diode Array Detector.: This study explores the use of LiChrospher^® 100 RP-18 (5 µm) for the rapid analysis of a new iron chelate fertilizer, showcasing its effectiveness in agricultural applications (Valverde et al., 2021).


• Application of Chemometric Approach for Development and Validation of High-Performance Liquid Chromatography Method for Estimation of Ropinirole Hydrochloride.: The research utilizes LiChrospher^® 100 RP-18 (5 µm) for the quantification of ropinirole in pharmaceutical formulations, highlighting its precision and robustness (Fatima et al., 2019).


• Quantification of Alprenolol and Propranolol in Human Plasma Using a Two-Dimensional Liquid Chromatography (2D-LC).: This paper demonstrates the application of LiChrospher^® 100 RP-18 (5 µm) in clinical settings for the analysis of beta-blockers in plasma, indicating its utility in pharmacokinetics (Gonçalves et al., 2017).


• Ultrasound-Assisted Surfactant-Enhanced Emulsification Micro-Extraction Followed by HPLC for Determination of Preservatives in Water, Beverages, and Personal Care Products.: The study highlights the use of LiChrospher^® 100 RP-18 (5 µm) for environmental and quality control analyses, demonstrating its versatility in various matrices (Jan-E et al., 2017).


• Development and Validation of Stability-Indicating HPLC Method for Determination of Cefpirome Sulfate.: This research focuses on the stability testing of cefpirome using LiChrospher^® 100 RP-18 (5 µm), emphasizing its reliability for pharmaceutical quality control (Zalewski et al., 2014).

Analysis Note

Application test: passes test
Pressure: ≤ 35 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
stability testing (performance): passes test
separation factor (Acetophenone/Phenol, selectivity test): 2.05 - 2.25
separation factor (Acetophenone/Cinnamic acid, selectivity test): 1.24 - 1.37
capacity factor (Toluene): 13.0 - 18.0

Legal Information

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable