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Merck

C-022

Supelco

Chlordiazepoxide solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C16H14ClN3O
Número de CAS:
Peso molecular:
299.75
EC Number:
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CNC1=C[N+]([O-])=C(c2ccccc2)c3cc(Cl)ccc3N1

InChI

1S/C16H14ClN3O/c1-18-15-10-20(21)16(11-5-3-2-4-6-11)13-9-12(17)7-8-14(13)19-15/h2-10,18-19H,1H3

InChI key

VVMUANXXDBQGMO-UHFFFAOYSA-N

General description

Chlordiazepoxide is a benzodiazepine sold under trade names such as Librax® or Klopoxid for short-term treatment of anxiety or management of acute alcohol withdrawal syndrome. This certified solution standard is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to urine drug testing and pharmaceutical research.

Application


  • Chlordiazepoxide hydrochloride in psychopharmacology: This research chemical is primarily used to investigate the pharmacokinetics and metabolic pathways of benzodiazepines. Studies such as those by Shayesteh et al. have explored the dissociation constants of benzodiazepines, aiding in the development of more effective anxiolytic treatments with a focus on minimizing side effects (Shayesteh et al., 2015).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Librax is a registered trademark of Valeant Pharmaceuticals North America LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Visite la Librería de documentos

Physiology. The perfect hypnotic?
Emmanuel Mignot
Science (New York, N.Y.), 340(6128), 36-38 (2013-04-06)
Patricia V Turner et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 51(1), 25-30 (2012-02-15)
The effect of chronic daily orogastric gavage with water (5 mL/kg) on behavior and physiology was evaluated in male Sprague-Dawley rats. Treatment groups included: unmanipulated control, restraint control, dry gavage, and gavage, with all rats singly housed (n = 9
D W Pittman et al.
Chemical senses, 37(5), 431-444 (2012-01-18)
Hyperphagia is a reported side effect of anxiolytic benzodiazepines such as chlordiazepoxide (CDP). Prior research has focused primarily on the ingestive responses to sweet or solid foods. We examined CDP effects on licking for normally accepted and avoided taste solutions
Kiersten S Smith et al.
Neuropharmacology, 63(2), 250-258 (2012-04-03)
GABA(A) receptor modulating drugs such as benzodiazepines (BZs) have been used to treat anxiety disorders for over five decades. In order to determine whether the same or different GABA(A) receptor subtypes are necessary for the anxiolytic-like action of BZs in
Padmanaban S Suresh et al.
Immunopharmacology and immunotoxicology, 34(4), 586-589 (2012-01-03)
Total and differential leucocyte count (TLC and DLC) in blood circulation influence humoral immune response and stress alters TLC and DLC by leucocyte misdistribution. Chlordiazepoxide, a widely used benzodiazepine anti-stress agent, is reported to reverse suppression of antibody response induced

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