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Merck

W224502

Sigma-Aldrich

Carvacrol

≥98%, FCC, FG

Sinónimos:

5-Isopropyl-2-methylphenol

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About This Item

Fórmula lineal:
(CH3)2CHC6H3(CH3)OH
Número de CAS:
Peso molecular:
150.22
FEMA Number:
2245
Beilstein/REAXYS Number:
1860514
EC Number:
Council of Europe no.:
2055
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
4.031
NACRES:
NA.21
organoleptic:
camphoraceous; woody; spicy
grade:
FG
Fragrance grade
Halal
Kosher
biological source:
synthetic
agency:
follows IFRA guidelines
meets purity specifications of JECFA
food allergen:
no known allergens

biological source

synthetic

Quality Level

grade

FG
Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines
meets purity specifications of JECFA

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

assay

≥98%

refractive index

n20/D 1.522 (lit.)

bp

236-237 °C (lit.)

mp

3-4 °C (lit.)

density

0.976 g/mL at 20 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

camphoraceous; woody; spicy

SMILES string

CC(C)c1ccc(C)c(O)c1

InChI

1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

InChI key

RECUKUPTGUEGMW-UHFFFAOYSA-N

Gene Information

human ... UGT1A4(54657)

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General description

Carvacrol is a monoterpene compound that can be used as a flavoring agent in food and cosmetics. It is one of the major volatile components in oregano essential oil.

Application


  • Carvacrol and Thymol Hybrids: Potential Anticancer and Antibacterial Therapeutics.: This review explores the synthesis, characterization, and biological activities of carvacrol and thymol hybrids, highlighting their potential as anticancer and antibacterial agents. The study emphasizes the significance of these compounds in developing novel therapeutic strategies (Peter et al., 2024).

  • Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.: This review investigates the role of essential oil constituents, including carvacrol, in modulating microglial activity. The findings suggest significant anti-inflammatory and neuroprotective effects, providing insights into their potential therapeutic applications in neuroinflammatory diseases (Stojanović et al., 2024).

  • Evidence of the Protective Role of Carvacrol in a Retinal Degeneration Animal Model.: This study demonstrates the protective effects of carvacrol in a retinal degeneration model. The results indicate that carvacrol can mitigate retinal damage and preserve retinal function, suggesting its potential as a therapeutic agent for retinal diseases (Inda et al., 2024).


Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

>212.0 °F

flash_point_c

> 100 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Los clientes también vieron

The natural antimicrobial carvacrol inhibits Campylobacter jejuni motility and infection of epithelial cells
Van Alphen LB, et al
PLoS ONE, 7(9), e45343-e45343 (2012)
Antimicrobial activity of carvacrol: current progress and future prospectives
Nostro A & Papalia T
Recent Patents on Anti-Cancer Drug Discovery, 7(1), 28-35 (2012)
Laura Higueras et al.
Carbohydrate polymers, 97(2), 262-268 (2013-08-06)
The aim of this work was to design new polymer-based systems exhibiting an adjustable loading capacity of carvacrol depending on the film formulation. For this purpose, biocomposite films were developed employing chitosan (CS) as the polymer matrix and hydroxypropyl-β-cyclodextrins (HP-βCDs)
Rachel Spiering et al.
PloS one, 7(9), e46336-e46336 (2012-10-11)
Tolerogenic dendritic cells (DCs) can induce regulatory T cells and dampen pathogenic T cell responses. Therefore, they are possible therapeutic targets in autoimmune diseases. In this study we investigated whether mouse tolerogenic DCs are induced by the phytonutrient carvacrol, a
Bo Tang et al.
Oncogene, 38(20), 3946-3961 (2019-01-30)
Although VPAC1 and its ligand vasoactive intestinal peptide (VIP) are important in gastrointestinal physiology, their involvements in progression of gastrointestinal tumor have not been explored. Here, we found that higher expression of VIP/VPAC1 was observed in gastric cancer compared to

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