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D80800

Sigma-Aldrich

N,N′-Dicyclohexylurea

98%

Sinónimos:

1,3-Dicyclohexylurea

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About This Item

Fórmula lineal:
C6H11NHCONHC6H11
Número de CAS:
2387-23-7
Peso molecular:
224.34
EC Number:
219-213-7
MDL number:
MFCD00003829
UNSPSC Code:
12352100
PubChem Substance ID:
24894186
NACRES:
NA.22

Quality Level

100

assay

98%

form

solid

mp

232-233 °C (lit.)

SMILES string

O=C(NC1CCCCC1)NC2CCCCC2

InChI

1S/C13H24N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h11-12H,1-10H2,(H2,14,15,16)

InChI key

ADFXKUOMJKEIND-UHFFFAOYSA-N

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000386477
0000367251
0000331384
0000331384
0000311024

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Stevan Pecic et al.
Bioorganic & medicinal chemistry letters, 22(1), 601-605 (2011-11-15)
Inhibition of soluble epoxide hydrolase (sEH) has been proposed as a new pharmaceutical approach for treating hypertension and vascular inflammation. The most potent sEH inhibitors reported in literature to date are urea derivatives. However, these compounds have limited pharmacokinetic profiles.
Xiang Fang et al.
American journal of physiology. Heart and circulatory physiology, 290(1), H55-H63 (2005-08-23)
Epoxyeicosatrienoic acids (EETs), lipid mediators synthesized from arachidonic acid by cytochrome P-450 epoxygenases, are converted by soluble epoxide hydrolase (SEH) to the corresponding dihydroxyeicosatrienoic acids (DHETs). Originally considered as inactive degradation products of EETs, DHETs have biological activity in some
Mozhgan Aghajanzadeh et al.
International journal of pharmaceutics, 586, 119546-119546 (2020-06-17)
In the present study, we successfully synthesized nanocarriers (NCs) based on Y-shaped miktoarm copolymers, Poly Ethylene Glycol-Lysine-(Poly Caprolactone)2 (PEG-Lys-PCL2), which were loaded by baicalein (B) through the nanoprecipitation process to assess their in-vitro and in-vivo properties. We applied various methods
Z Yu et al.
Circulation research, 87(11), 992-998 (2000-11-25)
The cytochrome P450-derived epoxyeicosatrienoic acids (EETs) have potent effects on renal vascular reactivity and tubular sodium and water transport; however, the role of these eicosanoids in the pathogenesis of hypertension is controversial. The current study examined the hydrolysis of the
Michele Aresta et al.
Dalton transactions (Cambridge, England : 2003), 39(30), 6985-6992 (2010-06-15)
NbCl(5) x (N,N'-dicyclohexylurea) 1a owns a distorted octahedral structure due to intramolecular NH...Cl bonding. The unit cell contains four units which are intermolecularly NH...Cl and NH...N bonded. An extended intramolecular network of H-bonding (N-H...Cl, CH...Cl, CH...N) causes the 3D self
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