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678937

Sigma-Aldrich

Tris[(1-benzyl-1H-1, 2, 3-triazol-4-yl)methyl]amine

97%

Sinónimos:

TBTA

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About This Item

Fórmula empírica (notación de Hill):
C30H30N10
Número de CAS:
510758-28-8
Peso molecular:
530.63
MDL number:
MFCD09265124
UNSPSC Code:
12161600
PubChem Substance ID:
24884865
NACRES:
NA.22

Quality Level

200

assay

97%

form

solid

reaction suitability

reagent type: ligand
reaction type: click chemistry

mp

132-143 °C

storage temp.

−20°C

SMILES string

C(N(Cc1cn(Cc2ccccc2)nn1)Cc3cn(Cc4ccccc4)nn3)c5cn(Cc6ccccc6)nn5

InChI

1S/C30H30N10/c1-4-10-25(11-5-1)16-38-22-28(31-34-38)19-37(20-29-23-39(35-32-29)17-26-12-6-2-7-13-26)21-30-24-40(36-33-30)18-27-14-8-3-9-15-27/h1-15,22-24H,16-21H2

InChI key

WKGZJBVXZWCZQC-UHFFFAOYSA-N

Categorías relacionadas

Application

A polytriazolylamine ligand which stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.

related product

Referencia del producto
Descripción
Precios

906301

BTTES

906328

BTTAA, ≥95%

hcodes

H413

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
WXBF4908V
WXBF0600V
WXBD8776V
MKCQ4523
MKCK8109

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Frank Iversen et al.
Theranostics, 3(3), 201-209 (2013-03-09)
Some of the main concerns with in vivo application of naked small interfering RNA are rapid degradation and urinary excretion resulting in a short plasma half-life. In this study we investigated how conjugation of polyethylene glycol (PEG) with variable chain
Xiangyu Zhang et al.
Therapeutic advances in medical oncology, 12, 1758835920947976-1758835920947976 (2020-10-01)
Aspirin has recently emerged as an anticancer drug, but its therapeutic effect on lung cancer has been rarely reported, and the mechanism of action is still unclear. Long-term use of celecoxib in large doses causes serious side effects, and it
Qian Wang et al.
Journal of the American Chemical Society, 125(11), 3192-3193 (2003-03-13)
The copper-catalyzed cycloaddition reaction between azides and alkynes functions efficiently in aqueous solution in the presence of a tris(triazolyl)amine ligand. The process has been employed to make rapid and reliable covalent connections to micromolar concentrations of protein decorated with either
Brent R Martin et al.
Nature methods, 9(1), 84-89 (2011-11-08)
The reversible thioester linkage of palmitic acid on cysteines, known as protein S-palmitoylation, facilitates the membrane association and proper subcellular localization of proteins. Here we report the metabolic incorporation of the palmitic acid analog 17-octadecynoic acid (17-ODYA) in combination with
Timothy R Chan et al.
Organic letters, 6(17), 2853-2855 (2004-08-28)
Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.
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