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Merck

67073

Sigma-Aldrich

7-Methylguanine

≥98.0% (HPLC)

Sinónimos:

2-Amino-6-hydroxy-7-methylpurine, Epiguanine

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About This Item

Fórmula empírica (notación de Hill):
C6H7N5O
Número de CAS:
Peso molecular:
165.15
Beilstein/REAXYS Number:
174245
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥98.0% (HPLC)

impurities

≤1% guanine

SMILES string

Cn1cnc2N=C(N)NC(=O)c12

InChI

1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)

InChI key

FZWGECJQACGGTI-UHFFFAOYSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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H A Billson et al.
Carcinogenesis, 30(4), 615-620 (2009-01-27)
Components of human diets may influence the incidence of colorectal adenomas, by modifying exposure or susceptibility to DNA-damaging alkylating agents. To examine this hypothesis, a food frequency questionnaire was used to assess the diet of patients recruited for a case-referent
Chie Tomikawa et al.
Nucleic acids research, 38(3), 942-957 (2009-11-26)
N(7)-methylguanine at position 46 (m(7)G46) in tRNA is produced by tRNA (m(7)G46) methyltransferase (TrmB). To clarify the role of this modification, we made a trmB gene disruptant (DeltatrmB) of Thermus thermophilus, an extreme thermophilic eubacterium. The absence of TrmB activity
Chiung-Wen Hu et al.
Chemical research in toxicology, 25(11), 2386-2392 (2012-10-05)
Areca nut is a carcinogen to humans and has been strongly associated with oral premalignant and malignant diseases. Previous studies speculated the presence of unknown direct-acting mutagens present in aqueous extracts of areca nut. We hypothesized whether any direct-acting alkylating
Kazuyoshi Tamae et al.
Cancer science, 100(4), 715-721 (2009-05-27)
Urinary 8-hydroxydeoxyguanosine (8-OH-dG) and 7-methylguanine (m7Gua) were measured by a column-switching high performance liquid chromatography method as markers of oxidative and methylating DNA damage, respectively. We investigated the associations between urinary 8-OH-dG or m7Gua and various lifestyle and demographic factors
Deepali Gupta et al.
Dalton transactions (Cambridge, England : 2003), (1)(1), 73-84 (2009-12-22)
In solution, unsubstituted guanine (GH2) is in a tautomeric equilibrium between 1H,7H-keto and 1H,9H-keto forms. Upon coordination with (dien)Pt(II), N9-bound mononuclear complex is preferentially formed. With excess (dien)Pt(II), the dinuclear complex [{Pt(dien)}2(GH-N7,N9)]3+ is formed at basic pH. The X-ray crystal

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