488712

Trimethyl(trifluoromethyl)silane

99%

• Sinónimos: (Trifluoromethyl)trimethylsilane, Ruppert’s Reagent, TFMTMS
• Fórmula lineal: (CH₃)₃SiCF₃
• Número de CAS: 81290-20-2
• Peso molecular: 142.19
• Beilstein/REAXYS Number: 4241868
• MDL number: MFCD00145454
• UNSPSC Code: 12352101
• PubChem Substance ID: 24872418
• NACRES: NA.22

Propiedades

• Quality Level: 200
• assay: 99%
• reaction suitability: reaction type: C-C Bond Formation
• bp: 54-55 °C (lit.)
• density: 0.962 g/mL at 20 °C (lit.)
• functional group: fluoro
• storage temp.: 2-8°C
• SMILES string: C[Si](C)(C)C(F)(F)F
• InChI: 1S/C4H9F3Si/c1-8(2,3)4(5,6)7/h1-3H3
• InChI key: MWKJTNBSKNUMFN-UHFFFAOYSA-N

Descripción

Application

Trimethyl(trifluoromethyl)silane can be used as a trifluoromethylating agent in the following processes:

• Conversion of N-(tert-butylsulfinyl)-imines to trifluoromethylated amines
• Conversion of trans-enones to trans-α-trifluoromethyl silyl ethers
• Trifluoromethylation of azomethine imines
• Conversion of H-phosphonates to CF₃-phosphonates
• Nucleophilic addition of the trifluoromethyl group to aldehydes and ketones.

Información de seguridad

• pictograms: GHS02
• signalword: Danger
• hcodes: H225,H261
• pcodes: P210 - P223 - P231 + P232 - P233 - P240 - P241
• Hazard Classifications: Flam. Liq. 2 - Water-react 2
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: 1.4 °F - closed cup
• flash_point_c: -17 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves