301450

4-Bromomethyl-6,7-dimethoxycoumarin

96%

• Fórmula empírica (notación de Hill): C₁₂H₁₁BrO₄
• Número de CAS: 88404-25-5
• Peso molecular: 299.12
• Beilstein/REAXYS Number: 4750487
• MDL number: MFCD00011570
• UNSPSC Code: 12352100
• PubChem Substance ID: 24858188
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 96%
• mp: 212-216 °C (lit.)
• fluorescence: λ_ex 322; λ_em 395 (Reaction product with acetic acid); λ_ex 354 nm; λ_em 435 nm in methanol
• functional group: bromo; ester
• SMILES string: COc1cc2OC(=O)C=C(CBr)c2cc1OC
• InChI: 1S/C12H11BrO4/c1-15-10-4-8-7(6-13)3-12(14)17-9(8)5-11(10)16-2/h3-5H,6H2,1-2H3
• InChI key: JGODLBJJCNQFII-UHFFFAOYSA-N

Descripción

Application

4-Bromomethyl-6,7-dimethoxycoumarin was used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It was also used as derivatization reagent:

• for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography
• in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
• for determination of carboxylic acids in chromatographic detection

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves