178497

L-Selectride^® solution

1.0 M in THF

• Sinónimos: Lithium tri-sec-butylborohydride solution
• Fórmula lineal: Li[CH(CH₃)CH₂CH₃]₃BH
• Número de CAS: 38721-52-7
• Peso molecular: 190.10
• Beilstein/REAXYS Number: 4007327
• MDL number: MFCD00011708
• UNSPSC Code: 12352000
• PubChem Substance ID: 24850749
• NACRES: NA.22

Propiedades

• form: liquid
• Quality Level: 200
• reaction suitability: reagent type: reductant
• concentration: 1.0 M in THF
• density: 0.89 g/mL at 25 °C
• SMILES string: [Li+].[H][B-](C(C)CC)(C(C)CC)C(C)CC
• InChI: 1S/C12H28B.Li/c1-7-10(4)13(11(5)8-2)12(6)9-3;/h10-13H,7-9H2,1-6H3;/q-1;+1
• InChI key: ACJKNTZKEFMEAK-UHFFFAOYSA-N

Descripción

General description

L-Selectride^® is an air and water sensitive solution mainly used as a bulky stereoselective hydride reducing agent.

Application

L-Selectride^™ solution may be used in the O-demethylation and N-demethylation of opium alkaloids and their derivatives.

L-Selectride^® can be used as a reagent for:

• The stereoselective reduction of ketone to alcohol.
• The selective demethylation of tert alcohol.

• Reducing agent

Reagent for:

• Enantioselective synthesis of a-amino acids via reduction of N-tert-butanesulfinyl ketimine esters
• Diastereoselective reduction reactions
• Hydride reduction of the Danishefsky pyranones
• Asymmetric reductive aldol reaction of enones with a-alkoxy aldehydes
• Synthesis of alkanols by carbonylation reactions

Packaging

View returnable container options.

Legal Information

6538 is a trademark of American Type Culture Collection

Selectride is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H250,H260,H314,H335,H351
• pcodes: P210 - P231 + P232 - P280 - P305 + P351 + P338 - P370 + P378 - P422
• Hazard Classifications: Carc. 2 - Flam. Liq. 2 - Pyr. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• target_organs: Respiratory system
• supp_hazards: EUH019
• Storage Class: 4.2 - Pyrophoric and self-heating hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 1.4 °F - closed cup
• flash_point_c: -17 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter