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150215

Sigma-Aldrich

9(10H)-Acridanone

99%

Sinónimos:

Acridone, 9,10-Dihydro-9-oxoacridine

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About This Item

Fórmula empírica (notación de Hill):
C13H9NO
Número de CAS:
578-95-0
Peso molecular:
195.22
Beilstein/REAXYS Number:
7104
EC Number:
209-434-7
MDL number:
MFCD00005019
UNSPSC Code:
12352100
PubChem Substance ID:
24848848
NACRES:
NA.22

Quality Level

100

assay

99%

form

solid

mp

>300 °C (lit.)

λmax

380 nm
399 nm (2nd)

SMILES string

O=C1c2ccccc2Nc3ccccc13

InChI

1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)

InChI key

FZEYVTFCMJSGMP-UHFFFAOYSA-N

Gene Information

human ... ABCB1(5243)

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Application

9(10H)-Acridanone (acridone) was used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate.

related product

Referencia del producto
Descripción
Precios

906115

2,7-Dibromoacridone

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
MKCV9083
MKCR2220
MKCQ6082
MKCQ0531
MKCN1370

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Giuseppe Manfroni et al.
Journal of medicinal chemistry, 52(10), 3354-3365 (2009-04-25)
We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral
Dadi Chen et al.
Biotechnology for biofuels, 13, 130-130 (2020-07-24)
Considerable interest has been expressed in the development of anaerobic digestion (AD) of straw to solve the environmental problems caused by the dumping and burning of straw and to generate clean energy. However, the poor biodegradability of straw and the
Anton V Dubrovskiy et al.
The Journal of organic chemistry, 77(24), 11232-11256 (2012-12-05)
A novel, efficient route to biologically and pharmaceutically important o-(dimethylamino)aryl ketones, acridones, acridinium salts, and 1H-indazoles has been developed starting from readily available hydrazones of aldehydes and o-(trimethylsilyl)aryl triflates. The reaction proceeds through arynes under mild conditions, tolerates a wide
Vishal P Zambre et al.
Journal of molecular graphics & modelling, 29(2), 229-239 (2010-08-10)
G-quadruplex structures of DNA represent a potentially useful target for anticancer drugs. Telomerase enzyme, involved in immortalization of cancer cells is inhibited by stabilization of G-quadruplex at the ends of chromosomes. Anthraquinone and acridone derivatives are promising G-quadruplex ligands as
Jacob M Goldberg et al.
Journal of the American Chemical Society, 134(14), 6088-6091 (2012-04-05)
Fluorescent probe pairs that can be selectively excited in the presence of Trp and Tyr are of great utility in studying conformational changes in proteins. However, the size of these probe pairs can restrict their incorporation to small portions of
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