SAB4700622

Monoclonal Anti-Ly6g-FITC antibody produced in rat

clone RB6-8C5, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Anti-Gr-1, Anti-Gr1, Anti-Ly-6G
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rat
• Quality Level: 100
• conjugate: FITC conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: RB6-8C5, monoclonal
• form: buffered aqueous solution
• species reactivity: mouse
• concentration: 1 mg/mL
• technique(s): flow cytometry: suitable
• isotype: IgG2b
• NCBI accession no.: XM_001475753.2
• UniProt accession no.: P35461
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Ly6g(546644)

Description

General description

Lymphocyte antigen 6 complex, locus G (Ly6G) is a 25kDa glycosylphosphatidylinositol (GPI)–anchored protein. It is encoded by the gene mapped to mouse chromosome 15. The encoded protein belongs to the Ly6/urokinase plasminogen activator receptor (uPAR) family. Ly6G is characterized with a “3 finger fold” motif stabilized by 4-5 disulfide bonds. Ly6G is expressed only in mice.

The rat monoclonal antibody RB6-8C5 detects Ly6G component of Gr-1 antigen, a commonly used surface marker of neutrophils.

Immunogen

Murine granulocytes

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Biochem/physiol Actions

The protein folds of lymphocyte antigen 6 complex, locus G (Ly6G) help to form a docking site for other molecules. Ly6G functions as a marker for neutrophils. The encoded protein might be implicated in the modulation of leukocyte migration.

Features and Benefits

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Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable