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43791

Sigma-Aldrich

2,2′-Dithiodipyridine

≥99.0% (GC)

Synonym(s):

2,2′-Dipyridyl disulfide

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About This Item

Empirical Formula (Hill Notation):
C10H8N2S2
CAS Number:
Molecular Weight:
220.31
Beilstein:
154629
EC Number:
MDL number:
UNSPSC Code:
12352112
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥99.0% (GC)

form

solid

mp

56-58 °C (lit.)
57-59 °C

storage temp.

2-8°C

SMILES string

S(Sc1ccccn1)c2ccccn2

InChI

1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H

InChI key

HAXFWIACAGNFHA-UHFFFAOYSA-N

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Other Notes

For the determination of sulfhydryl groups in biological materials

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Determination of sulfhydryl groups with 2,2'- or 4,4'-dithiodipyridine.
D R Grassetti et al.
Archives of biochemistry and biophysics, 119(1), 41-49 (1967-03-01)
Zita Hertelendi et al.
Antioxidants & redox signaling, 10(7), 1175-1184 (2008-03-12)
This study sought to characterize the relation between the oxidation of protein sulfhydryl (SH) groups and Ca2+-activated force production in the human myocardium. Triton-permeabilized left ventricular cardiomyocytes from donor hearts were exposed to an oxidative (2,2'-dithiodipyridine, DTDP) agent in vitro
Panagiotis Vagenas et al.
Journal of acquired immune deficiency syndromes (1999), 52(4), 433-442 (2009-09-26)
Although mucosal responses are important for preventing infections with HIV, the optimal strategies for inducing them remain unclear. To evaluate vaccine strategies targeting the oral mucosal lymphoid tissue inductive sites as an approach to provide immunity at distal sites, we
Claire Stines-Chaumeil et al.
The Biochemical journal, 395(1), 107-115 (2005-12-08)
Homotetrameric MSDH (methylmalonate semialdehyde dehydrogenase) from Bacillus subtilis catalyses the NAD-dependent oxidation of MMSA (methylmalonate semialdehyde) and MSA (malonate semialdehyde) into PPCoA (propionyl-CoA) and acetyl-CoA respectively via a two-step mechanism. In the present study, a detailed mechanistic characterization of the
Lisa R Jones et al.
Journal of the American Chemical Society, 128(20), 6526-6527 (2006-05-18)
The design, synthesis, and evaluation of conjugates of arginine-rich transporters and luciferin are described that release luciferin only after entry into cells that are stably transfected with luciferase. Each molecule of free luciferin that is released after entry generates a

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