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Sulfapyridine

VETRANAL®, analytical standard

Synonym(s):

4-Amino-N-[2-pyridyl]benzene sulfonamide, N1-(Pyridin-2-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):
C11H11N3O2S
CAS Number:
144-83-2
Molecular Weight:
249.29
Beilstein:
222065
EC Number:
205-642-7
MDL number:
MFCD00038036
UNSPSC Code:
41116107
PubChem Substance ID:
329753911
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2

InChI

1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)

InChI key

GECHUMIMRBOMGK-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide
Sulfapyridine is a metabolite of Sulfasalazine. It is an antibiotic and is mostly used in treating rheumatoid arthritis.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfapyridine (SPY) has been used as internal standard in HPLC method for determination of sulfonamides residue from honey samples.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361fd

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL5958
BCCK3249
BCCF2670
BCBZ7545
BCBR9634V

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A reliable high-performance liquid chromatography with ultraviolet detection for the determination of sulfonamides in honey.
Granja RH
Analytica Chimica Acta, 613(1), 116-119 (2008)
Cemalettin Alp et al.
Journal of enzyme inhibition and medicinal chemistry, 27(6), 818-824 (2011-12-23)
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I, II and human serum isozyme VI, with a series of tosylited aromatic amine derivatives was investigated. The K(I) ranges of compounds 1-14 and acetazolamide against hCA I
Christopher Chidley et al.
Nature chemical biology, 7(6), 375-383 (2011-04-19)
We introduce an approach for detection of drug-protein interactions that combines a new yeast three-hybrid screening for identification of interactions with affinity chromatography for their unambiguous validation. We applied the methodology to the profiling of clinically approved drugs, resulting in
Amirali Popat et al.
Angewandte Chemie (International ed. in English), 51(50), 12486-12489 (2012-11-07)
I want to break free: Mesoporous silica nanoparticles are functionalized with sulfasalazine (SZ; see scheme), a prodrug of 5-aminosalicylic acid (5-ASA) and sulfapyridine, to generate enzyme-responsive nanocarriers. In the presence of the colon-specific enzyme azo-reductase (orange), 5-ASA and sulfapyridine are
Hai Haham et al.
Environmental science & technology, 46(21), 11870-11877 (2012-10-02)
Sorption-desorption behavior of sulfapyridine was studied with three distinct soil types low in organic carbon with or without the introduction of exogenous dissolved organic matter (DOM). Experiments with bulk soils yielded sorption coefficients equivalent to those obtained with soils richer
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