164992

Sodium methoxide

reagent grade, 95%, powder

• Synonym(s): Sodium methylate
• Linear Formula: NaOCH₃
• CAS Number: 124-41-4
• Molecular Weight: 54.02
• Beilstein: 3592982
• EC Number: 204-699-5
• MDL number: MFCD00012179
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850111
• NACRES: NA.21

Properties

• grade: reagent grade
• Quality Level: 200
• vapor density: 1.1 (vs air)
• vapor pressure: 50 mmHg ( 20 °C)
• Assay: 95%
• form: powder
• autoignition temp.: 851 °F
• expl. lim.: 36 %
• SMILES string: [Na+].C[O-]
• InChI: 1S/CH3O.Na/c1-2;/h1H3;/q-1;+1
• InChI key: WQDUMFSSJAZKTM-UHFFFAOYSA-N

Description

General description

Sodium methoxide is a sodium alkoxide. Its reaction with unactivated aryl bromides in the presence of copper catalyst under various reaction conditions has been studied. It reacts with aryl halides in the presence of a palladium catalyst in DMF to afford arenes.

Application

Sodium methoxide has been used in the preparation of 5-(3-azidopropyl) uridine. It may be used in the synthesis of methyl 2-cyano-lup-3-hydroxy-2-en-28-oate (CN-BA), a 2-cyano derivative of betulinic acid (BA).

Sodium methoxide may be used as an alkali catalyst for the production of fatty acid methyl esters (biodiesel) from vegetable oils via transesterification.

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H228,H251,H290,H302,H314
• Precautionary Statements: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Flam. Sol. 1 - Met. Corr. 1 - Self-heat. 1 - Skin Corr. 1A
• Supplementary Hazards: EUH014
• Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 2
• Flash Point(F): 91.4 °F - closed cup
• Flash Point(C): 33 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves