702153

Hydroxyapatite

nanoparticles, dispersion, 10 wt. % in H₂O, <200 nm particle size (BET)

• Synonym(s): Calcium hydroxide phosphate, Calcium hydroxylapatite, Calcium hydroxyphosphate, Nano hydroxyapatatite, Pentacalcium hydroxide triphosphate
• Linear Formula: [Ca₅(OH)(PO₄)₃]_x
• CAS Number: 12167-74-7
• Molecular Weight: 502.31
• MDL number: MFCD00010904
• UNSPSC Code: 12352302
• PubChem Substance ID: 329762350
• NACRES: NA.23

Properties

• form: dispersion; nanoparticles
• Quality Level: 100
• contains: ≤0.025 wt. % dispersant (non-metal based)
• concentration: 10 wt. % in H₂O
• surface area: 14.3 m²/g , typical
• particle size: <200 nm (BET)
• pH: 4-6
• density: 1.038 g/mL at 25 °C
• SMILES string: [Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O
• InChI: 1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10
• InChI key: XYJRXVWERLGGKC-UHFFFAOYSA-D

Description

General description

Hydroxyapatite(HAP) is an osteoconductive bioceramic material which has uniqueability to form direct bonds with living tissues. It can be easily prepared byvarious techniques such as sol-gel, hydrothermal, multiple emulsion, biomimeticdeposition, and electrodeposition.

Application

Hydroxyapatite can be used as:

• An implant material for bone substitute due to its chemical similarity to the inorganic component of bone and osteo inductive properties.
• A vehicle for gene and drug delivery because of its encapsulation capacity and affinity to several drugs and proteins.
• A pH responsive particulate emulsifier.

Features and Benefits

• Biocompatible
• Osteoconductive
• Stable under physiological conditions
• High mechanical strength

Legal Information

Product of Engi-Mat Co.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable