Skip to Content
Merck
All Photos(1)

Documents

193283

Sigma-Aldrich

2-Amino-4-tert-butylphenol

98%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3)3CC6H3(NH2)OH
CAS Number:
1199-46-8
Molecular Weight:
165.23
EC Number:
214-844-4
MDL number:
MFCD00007698
UNSPSC Code:
12352100
PubChem Substance ID:
24851589
NACRES:
NA.22

Quality Level

100

Assay

98%

mp

160-163 °C (lit.)

SMILES string

CC(C)(C)c1ccc(O)c(N)c1

InChI

1S/C10H15NO/c1-10(2,3)7-4-5-9(12)8(11)6-7/h4-6,12H,11H2,1-3H3

InChI key

RPJUVNYXHUCRMG-UHFFFAOYSA-N

Related Categories

Application

2-Amino-4-tert-butylphenol can be used as a reactant to prepare:
  • 4-tert-butyl-2-[(pyridylmethylene)amino]phenol intermediates, which are used to synthesize biologically important 2-(pyridyl)benzoxazole derivatives.
  • Prolinamide phenols, as efficient hydrophobic organocatalysts for direct asymmetric aldol reaction aldehydes and ketones in water.
  • N-(2-hydroxy-4-tert-butylphenyl)-acetamide, a key intermediate to prepare uranylsalophene derivatives which can be used as selective receptors in anion sensitive membrane sensors.
  • Poly(2-amino-4-tert-butylphenol) [poly(2A-4TBP)] by electrochemical or chemical oxidative polymerization reaction.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Rationally designed 4-phenoxy substituted prolinamide phenols organocatalyst for the direct aldol reaction in water.
Zhang S-P, et al.
Tetrahedron Letters, 50(11), 1173-1176 (2009)
Rationally designed 4-phenoxy substituted prolinamide phenols organocatalyst for the direct aldol reaction in water
Z Shu-peng, et al.
Tetrahedron Letters, 50(11), 1173-1176 (2009)
Neutral anion receptors: Synthesis and evaluation as sensing molecules in chemically modified field effect transistors
Antonisse MMG, et al.
The Journal of Organic Chemistry, 62(26), 9034-9038 (1997)
Synthesis of 2-(2-, 3-, and 4-pyridyl) benzoxazoles by the reaction of phenolic schiff bases with thianthrene cation radical
Park Myeong Soon, et al.
Journal of Heterocyclic Chemistry, 39(6), 1279-1281 (2002)
Neutral anion receptors: synthesis and evaluation as sensing molecules in chemically modified field effect transistors.
Antonisse MMG, et al.
The Journal of Organic Chemistry, 62(26), 9034-9038 (1997)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service