SML1937

SN-6

≥98% (HPLC)

• Synonym(s): 2-[4-(4-Nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester, 4-Thiazolidinecarboxylic acid, 2-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]-, ethyl ester
• Empirical Formula (Hill Notation): C₂₀H₂₂N₂O₅S
• CAS Number: 415697-08-4
• Molecular Weight: 402.46
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD06798326
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(OCC)C1CSC(CC2=CC=C(OCC3=CC=C([N+]([O-])=O)C=C3)C=C2)N1
• InChI: 1S/C20H22N2O5S/c1-2-26-20(23)18-13-28-19(21-18)11-14-5-9-17(10-6-14)27-12-15-3-7-16(8-4-15)22(24)25/h3-10,18-19,21H,2,11-13H2,1H3
• InChI key: ZVYIJXLMBWCGHP-UHFFFAOYSA-N

Description

Application

SN-6 has been used as a selective Na⁺/Ca⁺⁺ exchanger (NCX) inhibitor to study its neuroprotective effects on axonal injury in mice.

Biochem/physiol Actions

SN-6 is a selective inhibitor of Na+/Ca++ exchanger (NCX) with some selectivity for the NCX1 isoform.

Selective Na+/Ca++ exchange (NCX) inhibitor

SN-6 is involved in safeguarding against hypoxia and reoxygenation‐induced cell damage in renal tubular cells.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable