I1774
Iturin A from Bacillus subtilis
≥95% (HPLC), suitable for microbiological culture
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product name
Iturin A from Bacillus subtilis, ≥95% (HPLC)
biological source
Bacillus subtilis
Quality Level
Assay
≥95% (HPLC)
form
powder
technique(s)
microbiological culture: suitable
color
white to yellow
solubility
ethanol: soluble 9.80-10.20 mg/mL
antibiotic activity spectrum
fungi
Mode of action
cell membrane | interferes
storage temp.
2-8°C
Application
Iturin A was used in the study of Bacillomycin D (an iturin with antifungal activity against Aspergillus flavus).
Biochem/physiol Actions
IturinA exhibits strong antifungal activity against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell forming ion conducting pores. Its mode of action could be attributed to its interaction with sterols and phospholipids. The compound causes the release of exo-vesicles from human erythrocytes.
Other Notes
A family of lipopeptides characterized by a heptapeptide cyclized with a C13-C17 β-amino fatty acid. Composed mainly of C14-C15 β-amino acids.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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