E1260

L-Ethionine

≥99% (TLC)

• Synonym(s): L-2-Amino-4-(ethylthio)butyric acid
• Linear Formula: C₂H₅SCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 13073-35-3
• Molecular Weight: 163.24
• NACRES: NA.26
• PubChem Substance ID: 24894397
• UNSPSC Code: 12352209
• EC Number: 235-966-4
• MDL number: MFCD00002626

Properties

• Product Name: L-Ethionine, ≥99% (TLC)
• Quality Segment: 100
• assay: ≥99% (TLC)
• form: powder
• color: white
• mp: 280 °C (dec.) (lit.)
• storage temp.: −20°C
• SMILES string: CCSCC[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
• InChI key: GGLZPLKKBSSKCX-YFKPBYRVSA-N

Description

Biochem/physiol Actions

An analog of methionine that interferes with the normal methylation of DNA and other methylation pathways, and induces pancreatic toxicity and liver cancer. However, in animal studies, it has also been shown to act synergistically with methionine-depletion to block the growth and metastasis of methionine-dependent tumors.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves