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51471C

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Iscove′s Modified Dulbecco′s Medium

liquid

Synonym(s):

IMDM

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About This Item

MDL number:
MFCD00217469
UNSPSC Code:
12352207
NACRES:
NA.75

description

for research or for further manufacturing use
with 4.0 mM L-glutamine, with 25 mM HEPES

sterility

sterile

form

liquid

technique(s)

cell culture | hybridoma: suitable
cell culture | mammalian: suitable
cell culture | stem cell: suitable

components

phenol red: 15.93 mg/L
NaHCO3: 3024 mg/L
L-glutamine: 582 mg/L
HEPES: 5958 mg/L
sodium pyruvate: 110 mg/L

shipped in

ambient

storage temp.

2-8°C

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General description

Iscove′s Modified Dulbecco′s Medium (IMDM) is a modification of the Dulbecco′s modified Eagle′s medium (DME) and contains additional amino acids, vitamins, selenium, sodium pyruvate, HEPES buffer, and potassium nitrate. This medium supports the growth of murine B lymphocytes, T lymphocytes, hemopoietic tissue from bone marrow, B cells stimulated with lipopolysaccharide, and other hybrid cells.

Application

Iscove′s Modified Dulbecco′s Medium has been used for the differentiation of pluripotent stem cells (PSCs).

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Christine Bourgeois et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(25), 8691-8696 (2008-06-20)
A model of chemical thymectomy by inducible Rag ablation was used to study peripheral T cell homeostasis. Induction of Rag ablation was efficient and complete, leading to cessation of thymic T cell production within 3-4 weeks. The decay of peripheral
André-Guilhem Calas et al.
Biomolecules, 10(6) (2020-06-10)
(1) Background: Human exposure to organophosphorus compounds employed as pesticides or as chemical warfare agents induces deleterious effects due to cholinesterase inhibition. One therapeutic approach is the reactivation of inhibited acetylcholinesterase by oximes. While currently available oximes are unable to
Gustav Nilsonne et al.
Behavioral and brain functions : BBF, 7, 47-47 (2011-11-22)
Recent advances in cell biology and gene regulation suggest mechanisms whereby associative learning could be performed by single cells. Therefore, we explored a model of classical conditioning in human macrophages in vitro. In macrophage cultures, bacterial lipopolysaccharide (LPS; unconditioned stimulus)
Florian A Salomons et al.
Molecular and cellular biology, 29(7), 1774-1785 (2009-01-23)
Conditions causing an increase in misfolded or aberrant proteins can impair the activity of the ubiquitin/proteasome system (UPS). This observation is of particular interest, given the fact that proteotoxic stress is closely associated with a large variety of disorders. Although

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