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Sigma-Aldrich

Lycopene, Redivivo™

10% FS, ~10% in corn oil, ≥95.0% (sum of isomers)

Synonym(s):

Lycopene, dispersion

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About This Item

Empirical Formula (Hill Notation):
C40H56
CAS Number:
502-65-8
Molecular Weight:
536.87
EC Number:
232-281-2
MDL number:
MFCD00017350
UNSPSC Code:
12352211
PubChem Substance ID:
329755000
NACRES:
NA.47

Assay

≥95.0% (sum of isomers)

contains

≤2.5% α-Tocopherol as stabilizer

concentration

~10% in corn oil

storage temp.

2-8°C

SMILES string

C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C

InChI

1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

InChI key

OAIJSZIZWZSQBC-GYZMGTAESA-N

Biochem/physiol Actions

Lycopene is a red phytochemical pigment found in tomatoes. The main carotenoid in human plasma, it is a highly potent antioxidant, the most efficient biological quencher of singlet oxygen, associated with decreased risk of cancer and cardiovascular diseases. Lycopene enhances gap junction communication between cells via upregulation of connexin 43 and reduces profileration of cancer cells in culture. Inhibits cholesterol synthesis and enhances low-density lipoprotein degradation. Lycopene in skin sacrificially protects against UV-induced degradation of β-carotene.

Other Notes

REDIVIVO is a non-toxic, stable formulation of lycopene (10% dispersion in corn oil) that offers convenient handling and is dust-free.

Legal Information

Redivivo is a trademark of DSM Nutritional Products AG

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Precautionary Statements

P280 - P302 + P352

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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USP

USP

1148806

Corn oil

β-Carotene synthetic, ≥93% (UV), powder

Sigma-Aldrich

C9750

β-Carotene

Corn oil analytical standard

Supelco

47112-U

Corn oil

Tamoxifen ≥99%

Sigma-Aldrich

T5648

Tamoxifen

P Di Mascio et al.
Archives of biochemistry and biophysics, 274(2), 532-538 (1989-11-01)
Lycopene, a biologically occurring carotenoid, exhibits the highest physical quenching rate constant with singlet oxygen (kq = 31 X 10(9) M-1 s-1), and its plasma level is slightly higher than that of beta-carotene (kq = 14 X 10(9) M-1 s-1).
Xiang-Dong Wang
The American journal of clinical nutrition, 96(5), 1214S-1222S (2012-10-12)
The beneficial effects of a high intake of tomatoes and tomato products on the risk of certain chronic diseases have been presented in many epidemiologic studies, with the suggestion that lycopene (a major carotenoid in tomatoes) is a micronutrient with
Joanna Lado et al.
Physiologia plantarum, 154(4), 469-484 (2015-02-14)
The distinctive color of red grapefruits is due to lycopene, an unusual carotene in citrus. It has been observed that red 'Star Ruby' (SR) grapefruits grown inside the tree canopy develop a more intense red coloration than those exposed to
J D Ribaya-Mercado et al.
The Journal of nutrition, 125(7), 1854-1859 (1995-07-01)
This placebo-controlled study examined in healthy women the effects of ingestion of a single large dose of beta-carotene (120 mg) on the concentrations of beta-carotene and lycopene in plasma and skin, and the effects of UV light exposure on the
Wilhelm Stahl et al.
Skin pharmacology and applied skin physiology, 15(5), 291-296 (2002-09-20)
Upon exposure to UV light photooxidative reactions are initiated which are damaging to biomolecules and affect the integrity of cells and tissues. Photooxidative damage plays a role in pathological processes and is involved in the development of disorders affecting the
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