95197

Kojic acid

analytical standard

• Synonym(s): 2-Hydroxymethyl-5-hydroxy-γ-pyrone, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone
• Empirical Formula (Hill Notation): C₆H₆O₄
• CAS Number: 501-30-4
• Molecular Weight: 142.11
• UNSPSC Code: 85151701
• NACRES: NA.24
• PubChem Substance ID: 329770427
• EC Number: 207-922-4
• Beilstein/REAXYS Number: 120895
• MDL number: MFCD00006580

Properties

• grade: analytical standard
• Quality Segment: 100
• assay: ≥99.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• mp: 152-155 °C (lit.)
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• SMILES string: OCC1=CC(=O)C(O)=CO1
• InChI: 1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
• InChI key: BEJNERDRQOWKJM-UHFFFAOYSA-N

Description

General description

Kojic acid, a tyrosinase inhibitor, is produced by several fungi species, including Aspergillus oryzae. It exhibits skin-lightening property, due to its ability to chelate the copper-containing enzyme tyrosinase in the formation of melanin. Kojic acid is also commonly used as a whitening agent in regular cosmetics, bleaching cosmetics, etc. It is found to be a therapeutic agent and helps in preventing pigmentation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Kojic acid may be used as an analytical reference standard for the determination of the analyte in skin whitening cosmetics and bleaching cosmetics using high performance liquid chromatography with UV detection (HPLC-UV).

Biochem/physiol Actions

Tyrosinase inhibitor.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable