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Benalaxyl

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H23NO3
CAS Number:
Molecular Weight:
325.40
Beilstein:
3001587
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

COC(=O)C(C)N(C(=O)Cc1ccccc1)c2c(C)cccc2C

InChI

1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3

InChI key

CJPQIRJHIZUAQP-UHFFFAOYSA-N

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General description

Benalaxyl is a phenylamide fungicide used for the control of Oomycetes, particularly fungi of the family Peronosporaceae, Phythophthora plasmopara, and Pythium spp. Benalaxyl acts by inhibiting RNA polymerization (polymerase complex I).
Benalaxyl is a systemic fungicide belonging to the acylalanine family. It is found to be active against Oomycetes belonging to Peronosporaceae family.

Application

Benalaxyl may be used as a fungicide reference standard for the determination of the analyte:
  • In rabbit plasma by a chiral high-performance liquid chromatography method with a diode array detector (HPLC-DAD).
  • In vegetable samples by gas chromatography-tandem mass spectrometry (GC-MS-MS).

Benalaxyl may be used as a reference standard for the determination of the analyte in water and wine samples using enzyme linked immunosorbent assay (ELISA).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Ping Zhang et al.
Chirality, 23(2), 93-98 (2010-06-15)
Benalaxyl (BX), methyl-N-phenylacetyl-N-2,6-xylyl alaninate, is a potent acylanilide fungicide and consist of a pair of enantiomers. The stereoselective metabolism of BX was investigated in rat and rabbit microsomes in vitro. The degradation kinetics and the enantiomer fraction (EF) were determined
Gopinath C Nallani et al.
Regulatory toxicology and pharmacology : RTP, 84, 26-34 (2016-12-21)
The in vitro comparative animal metabolism study is now a data requirement under EU Directive 1107/2009 for registration of plant protection products. This type of study helps determine the extent of metabolism of a chemical in each surrogate species and whether
Separation of Benalaxyl and its metabolites by high-performance liquid chromatography.
P Cabras et al.
Journal of chromatography, 391(1), 334-337 (1987-03-27)
Xu Gu et al.
Chirality, 20(2), 125-129 (2007-12-20)
The stereoselective degradation of the racemic benalaxyl in vegetables such as tomato, tobacco, sugar beet, capsicum, and the soil has been investigated. The two enantiomers of benalaxyl in the matrix were extracted by organic solvent and determined by validated chiral
Development of an enzyme-linked immunosorbent assay for benalaxyl and its application to the analysis of water and wine.
Giraudi G, et al.
Analytica Chimica Acta, 392(1), 85- 94 (1999)

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