23258

2,2,2-Trichloroethyl chloroformate

purum, ≥98.0% (NT)

• Synonym(s): 2,2,2-Trichloroethoxycarbonyl chloride
• Linear Formula: ClCOOCH₂CCl₃
• CAS Number: 17341-93-4
• Molecular Weight: 211.86
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 329752403
• EC Number: 241-363-7
• Beilstein/REAXYS Number: 970619
• MDL number: MFCD00000810
• Assay: ≥98.0% (NT)

Properties

• vapor pressure: 0.06 psi ( 20 °C)
• Quality Segment: 200
• grade: purum
• assay: ≥98.0% (NT)
• refractive index: n20/D 1.471
• bp: 171-172 °C (lit.)
• density: 1.539 g/mL at 25 °C (lit.)
• functional group: chloro
• storage temp.: 2-8°C
• SMILES string: ClC(=O)OCC(Cl)(Cl)Cl
• InChI: 1S/C3H2Cl4O2/c4-2(8)9-1-3(5,6)7/h1H2
• InChI key: LJCZNYWLQZZIOS-UHFFFAOYSA-N

Description

Application

2,2,2-Trichloroethyl chloroformate was used as:

• derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples
• starting reagent during the synthesis of 6-nor-9,10-dihydrolysergic acid methyl ester (IV)
• reagent during N-demethylation of dextromethorphan
• protecting group reagent for amines and alcohols

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H314,H331
• pcodes: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter