M29304

N-Methylaniline

98%

• Synonym(s): Monomethylaniline
• Linear Formula: C₆H₅NHCH₃
• CAS Number: 100-61-8
• Molecular Weight: 107.15
• Beilstein: 741982
• EC Number: 202-870-9
• MDL number: MFCD00008283
• UNSPSC Code: 12352100
• PubChem Substance ID: 24896781
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• refractive index: n20/D 1.571 (lit.)
• bp: 196 °C (lit.)
• mp: −57 °C (lit.)
• density: 0.989 g/mL at 25 °C (lit.)
• SMILES string: CNc1ccccc1
• InChI: 1S/C7H9N/c1-8-7-5-3-2-4-6-7/h2-6,8H,1H3
• InChI key: AFBPFSWMIHJQDM-UHFFFAOYSA-N

Description

Application

N-Methylaniline is a general reagent used:

• In the preparation of phosphoramidite ligands for the rhodium-catalyzed asymmetric hydroboration.
• As a formylating reagent in the C3-selective formylation of indoles.
• In the synthesis of a rhodol-based fluorescent probe, HKGreen-3, for sensing peroxynitrite.
• As a key starting material in the synthesis of AKT (protein kinase B) inhibitor-IV.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H301 + H311 + H331,H319,H373,H410
• Precautionary Statements: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P314
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - STOT RE 2 Oral
• Target Organs: Liver,spleen,Bone marrow
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): 185.0 °F - closed cup
• Flash Point(C): 85 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves