Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
305995
2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite
97%
Synonym(s):
Bis(diisopropylamino)(2-cyanoethoxy)phosphine
About This Item
Recommended Products
Quality Level
Assay
97%
form
liquid
refractive index
n20/D 1.470 (lit.)
bp
100 °C/0.5 mmHg (lit.)
density
0.949 g/mL at 25 °C (lit.)
functional group
amine
nitrile
storage temp.
−20°C
SMILES string
CC(C)N(C(C)C)P(OCCC#N)N(C(C)C)C(C)C
InChI
1S/C15H32N3OP/c1-12(2)17(13(3)4)20(19-11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3
InChI key
RKVHNYJPIXOHRW-UHFFFAOYSA-N
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Application
- in preparation of prosphoramidite reagent, required for synthesis of 12-mer oligodeoxynucleotide[1]
- as phosphorylating agent in synthesis of 1,2-diacyl-sn-glycerophosphatidylserine[2]
- in situ preparation of deoxyribonucleoside phosphoramidites[3]
- in preparation of 2′-deoxy-2′-fluoro-3′-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-5′-O-(4-methoxytrityl)-4′-thio-β-D-arabinouridine and 1-(3-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-2-deoxy-2-fluoro-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-arabinofuranosyl)-thymine[4]
- as reagent for synthesizing phosphitylated nucleotides[5]
related product
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 3 - Skin Sens. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
119.3 °F - closed cup
Flash Point(C)
48.5 °C - closed cup
Personal Protective Equipment
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How is shipping temperature determined? And how is it related to the product storage temperature?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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In 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite reagent is there any stabilizer is added! what is the stabilizer added for the storage of the above reagent.
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There is no stabilizer added, but the product is handled and stored under nitrogen due to its moisture sensitivity.
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