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394882

Sigma-Aldrich

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

>97%

Sinónimos:

MTBSTFA

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About This Item

Fórmula lineal:
CF3CON(CH3)Si(CH3)2C(CH3)3
Número de CAS:
77377-52-7
Peso molecular:
241.33
Beilstein:
3606546
Número MDL:
MFCD00009671
Código UNSPSC:
12352001
ID de la sustancia en PubChem:
24864624
NACRES:
NA.22

grado

derivatization grade

Nivel de calidad

200

Ensayo

>97%

Formulario

liquid

índice de refracción

n20/D 1.402 (lit.)

bp

172-175 °C (lit.)

densidad

1.036 g/mL at 25 °C (lit.)

grupo funcional

amine
fluoro

temp. de almacenamiento

2-8°C

cadena SMILES

CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C

InChI

1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3

Clave InChI

QRKUHYFDBWGLHJ-UHFFFAOYSA-N

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Descripción general

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a highly reactive silylating reagent commonly used for silyation of carboxylic acids, alcohols, amines, and thiols. It is also used as a protection, deprotection reagent.

Aplicación

N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide (MTBSTFA) can be used:
  • As a derivatizing agent in the GC-MS analysis of hydroxylated fluorenes and in the GC analysis of amino acids.
  • As an efficient silylating agent for different alcohols, thiols, phenols, carboxylic acids, amines, and amides.
  • To functionalize multi-walled carbon nanotubes (MWCNTs) with polar groups.
MTBSTFA is reportedly much less moisture-sensitive than other silylating reagents used for GLC derivatization.

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Pictogramas

Flame
GHS02

Palabra de señalización

Warning

Frases de peligro

H226

Clasificaciones de peligro

Flam. Liq. 3

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

113.0 °F - closed cup

Punto de inflamabilidad (°C)

45 °C - closed cup

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
BCCK2208
BCCH3121
BCCD5162
BCBZ6312
BCBV5549

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Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

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Determination of β-blockers and β-agonists using gas chromatography and gas chromatography-mass spectrometry-a comparative study of the derivatization step
Caban M, et al.
Journal of Chromatography A, 1218(44), 8110-8122 (2011)
Evaluating MTBSTFA derivatization reagents for measuring naphthenic acids by gas chromatography-mass spectrometry
Rozlyn YF,et al.
Analytical Methods, 2, 765-770 (2010)
Silylation of multi-walled carbon nanotubes
Aizawa M, et al.
Chemical Physics Letters, 368(1-2), 121-124 (2003)
High-throughput analysis of selected urinary hydroxy polycyclic aromatic hydrocarbons by an innovative automated solid-phase microextraction
Stefano D,et al.
Molecules (Basel), 23, 1869-1869 (2018)
Two stage derivatization with N-(tert.-butyldimethylsilyl)-N-methyl-trifluoroacetamide (MTBSTFA) and N-methyl-bis-(trifluoroacetamide)(MBTFA) for the gas-chromatographic analysis of OH-, SH-and NH-compounds
Schoene K, et al.
Fresenius Journal of Analytical Chemistry, 348(5-6), 364-370 (1994)
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